Results 111 to 120 of about 15,298 (264)

Influence of oxyhydrogen gas retrofit into two-stroke engine on emissions and exhaust gas temperature variations. [PDF]

Heliyon
Kamarudin R, Ang YZ, Topare NS, Ismail MN, Mustafa KF, Gunnasegaran P, Abdullah MZ, Mazlan NM, Badruddin IA, Zedan ASA, Baig RU, Sultan SM.   +11 more
europepmc   +1 more source

Fully Humanized Bispecific T Cell Engager Shows Potent Activity in Central Nervous System and Peripheral Tumors

Advanced Science, EarlyView.
This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy, Angela Martin‐Regalado, Benedikt E. Haupt, Jacob R. Pogue, Aditi Thakur, Manuel Fierro Cota, Markella Zannikou, Sol Misener, Vera P. Krymskaya, Kathleen McCortney, Jason Miska, Craig Horbinski, Dmitri Simberg, Maciej S. Lesniak, Charles D. James, Roger Stupp, Irina V. Balyasnikova   +16 more
wiley   +1 more source

Engineered extracellular vesicles for ischemic stroke treatment

The Innovation, 2023
Huitong Ruan, Yongfang Li, Dandan Zheng, Lianfu Deng, Gang Chen, Xingcai Zhang, Yaohui Tang, Wenguo Cui   +7 more
openaire   +3 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Prior-Knowledge-Guided Graph Attention Network for Fault Diagnosis of Engine Valve Clearance. [PDF]

Sensors (Basel)
Li M, Wen J, Yang X, Hu Y, Li X, Shi Z.
europepmc   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Pairing taguchi based design of experiment with response surface methodology for diesel engine performance optimization using biodiesel-magnesium oxide nanoparticles blends. [PDF]

PLoS One
Zafar MU, Mohamed HG, Alnamasi K, Alsharif AMA, Bashir MN.   +4 more
europepmc   +1 more source

Imaging gas in a combustion engine with high-energy X-ray Compton scattering. [PDF]

J Synchrotron Radiat
Mizuno Y, Suzuki H, Tsuji N, Oguchi T, Matsubara G, Yamase H, Sakurai Y.   +6 more
europepmc   +1 more source