Results 241 to 250 of about 127,749 (338)

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

Advanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen, YuWei Zhou, LongXiang Sheng, FangYing Mai, YuXuan Ding, ShiRan Hong, JiaXin Wu, JiaKai Pi, GuangMei Yan, YiJun Huang, JingJing Duan, Xuefeng Hua, Wei Yin   +12 more
wiley   +1 more source

Investigation of diesel engine characteristics under pilot injection mode using diesel-DTBP blends. [PDF]

Sci Rep
Dave H, Choksi H, Siddiqui MIH, Dixit S, Markiewicz A.   +4 more
europepmc   +1 more source

Lubrication of a crosshead-pin bearing in a two-stroke cycle engine. Analysis of the bearing with an elliptical bearing surface.

, 1989
Yutaro Wakuri, Toshiro Hamatake, Mitsuhiro Soejima   +2 more
openalex   +2 more sources

Toward the Clinical Translation of Implantable Brain–Computer Interfaces for Motor Impairment: Research Trends and Outcome Measures

Advanced Science, EarlyView.
Implantable brain–computer interfaces (iBCIs) are rapidly approaching clinical translation. This review maps key trends in the development of iBCIs and highlights the lack of standardised clinical outcome measures. It discusses a proposed framework for the selection of outcome measures in clinical trials and introduces a new international registry of ...
Esmee Dohle, Eleanor Swanson, Luka Jovanovic, Suraya Yusuf, Lucy Thompson, Hugo Layard Horsfall, William Muirhead, Luke Bashford, Jamie Brannigan   +8 more
wiley   +1 more source

Optimizing engine operating parameters for enhanced performance in a combustion-enhanced ternary-fuelled compression ignition engine. [PDF]

Sci Rep
Muniyappan S, Krishnaiah R.
europepmc   +1 more source

Study on the Vibration and Strength of the Long Stroke Diesel Engine Crank Shaftings

, 1988
Shigehiro Homori, Minoru Kamata, Yasuo Sasaki   +2 more
openalex   +2 more sources

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Production and utilization of hydrogen enriched fifth generation biofuel in LTC engines with reformed EGR. [PDF]

Sci Rep
Ramalingam K, Abdullah MZ, Elumalai PV, Reddy MV, Yafang Y, Prabhakar S, Kamakshi Priya K.   +6 more
europepmc   +1 more source

Limiting delivery ratio curves of crankcase-scavenged 2-stroke cycle engines (By throttling the inlet port)

, 1986
Itaru Fukutani, Eiichi Watanabe
openalex   +2 more sources

Epigenetic Regulation of DAPK1 and Netrin‐1 Drives Diabetic Encephalopathy

Advanced Science, EarlyView.
This study identifies a microRNA (miR)‐216a‐5p/death‐associated protein kinase 1 (DAPK1)/hepatocyte nuclear factor 1 homeobox A (HNF1A)/Netrin‐1 signaling axis in diabetic encephalopathy (DE). In leptin receptor‐deficient (db/db) and streptozotocin (STZ)‐induced diabetic mice, reduced miR‐216a‐5p increases DAPK1 expression, disrupting HNF1A binding to ...
Yang Zhou, Jia‐Xin Kou, Kai Zheng, Zi‐Xuan Guo, Hong‐Wei Fan, Wen‐Lian Li, Lu‐Lu Chu, Jing‐Wen Yin, Li‐Jie Liu, Zhi‐Gao Xiang, Feng Hu, Kai Shu, Ling‐Qiang Zhu, Dan Liu   +13 more
wiley   +1 more source