Results 51 to 60 of about 8,744,295 (311)

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Ferdinand Bohmann, Christian Foerch (149410), Edelgard Lindhoff-Last (149408), Ferdinand Bohmann (149406), Mirceska, Ana, Ana Mirceska, Förch, Christian, Waltraud Pfeilschifter, Pfeilschifter, Josef (Prof. Dr.), Bohmann, Ferdinand, Edelgard Lindhoff-Last, Waltraud Pfeilschifter (149411), Helmuth Steinmetz, Steinmetz, Helmuth, Christian Foerch, Helmuth Steinmetz (149409), Pfeilschifter, Waltraud, Josef Pfeilschifter, Josef Pfeilschifter (92946), Ana Mirceska (149407), Lindhoff-Last, Edelgard   +20 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Bio-electrical impedence plethysmography-designing an efficient non-invasive electrode for cardiac rate analysis

International Journal of Endorsing Health Science Research, 2013
Cardiac rate analysis is constituted as one of the most essential parts of physiological patient monitoring. In this research paper, it has been investigated that electrical impedance plethysmography is the most conducive technique for this purpose.
Daniya Umer, Ghanwa Ellahi, Warda Ellahi, Saba Ayub, Zia Mohy Ud Din   +4 more
doaj   +1 more source

The Royal Blackburn Hospital, Acute Stroke Unit [PDF]

Stroke Unit ...
Ramsden, Victoria, Philip, Sheeba J.
core   +1 more source

Role of SH levels and markers of immune response in the stroke [PDF]

, 2013
Background. Sulfhydryl groups (SH) are considered a key factor in redox sensitive reaction of plasma, and their modification could be considered an expression of abnormal generation of oxygen free radicals. Methods. Fifty consecutive patients with acute
Arru, Giannina, Gervasoni Jacopo, D’Addessi A, Minucci, Angelo, Fois, Maria Laura, Sotgiu, Stefano, Schiattarella Arcangelo, Cocci A, Angeletti, Silvia, Schiattarella, Arcangelo, Musumeci, Maria, Gambaro Giovanni, Persichilli S, Fois ML, Persichilli, Silvia, Musumeci, Salvatore, Primiano, Aniello, Ferraro Pm, Minucci A, Musumeci M, Angeletti S, Gambaro, Giovanni, Gervasoni, Jacopo, Ferraro, Pietro Manuel, Persichilli Silvia, Musumeci S., Primiano Aniello   +26 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Haemodilution in acute stroke: results of the Italian haemodilution trial.

, 1988
In a multicentre clinical trial 1267 patients with hemispheric stroke of duration 12 h or less and haematocrit of 35% or more were prospectively randomised to either haemodilution (by venesection and replacement of the same volume of dextran 40 in saline
Italian Acute Stroke Study Group, FABRIZI, Gian Maria   +1 more
core   +1 more source

A multicentre observational study of presentation and early assessment of acute stroke [PDF]

, 2002
Objective To investigate delays in the presentation to hospital and evaluation of patients with suspected stroke.Design Multicentre prospective observational study.Setting 22 hospitals in the United Kingdom and Dublin.Participants 739 patients with ...
Kalra, L, Vass, RI, Brown, M M, ?, ?, Harraf, F, Lees, KR, Lees, K R, Acute Stroke Intervention Study Gr, Sharma, A K, Sharma, AK, Vass, R I, Brown, MM   +11 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Stroke etiology and white matter burden in women with and without migraine

The Journal of Headache and Pain
Background Women with migraine, especially with aura (MA), have a higher risk of white matter hyperintensities (WMH) and ischemic stroke. We aimed to assess differences in stroke etiology between women with and without migraine and the impact of migraine
Anne E. Wilms, Nelleke van der Weerd, Thijs W. van Harten, Katie M. Linstra, Hendrikus J. A. van Os, Irene de Boer, Mark C. Kruit, Antoinette Maassen van den Brink, Marieke J. H. Wermer, Gisela M. Terwindt, On behalf of the CREW consortium   +10 more
doaj   +1 more source