Results 1 to 10 of about 11,256,402 (404)

Identification of Stromal Cells in Spleen Which Support Myelopoiesis [PDF]

Frontiers in Cell and Developmental Biology, 2019
Stromal cells in spleen organize tissue into red pulp, white pulp and marginal zone, and also interact with hematopoietic cells to regulate immune responses.
Hong Kiat Lim, Hong Kiat Lim, Helen C. O’Neill   +2 more
doaj   +4 more sources

Low dose IFNγ remodels enhancer landscape to potentiate mesenchymal stromal cell activation. [PDF]

Stem Cell Res Ther
Lin J, Ruan D, Hu Q, Cao X, Zhou W, Hu S.   +5 more
europepmc   +3 more sources

Sexual dimorphism in colon is mediated by an androgen-IL33⁺ stromal cell axis. [PDF]

Cell Biosci
Wang H, Jing B, Zou J, Lan T, Hu M, Lin L, Cheng H, Zhou R.   +7 more
europepmc   +3 more sources

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

iScience, 2021
Summary: Melanoma is an aggressive skin cancer developing from melanocytes, frequently resulting in metastatic disease. Melanoma cells utilize amoeboid migration as mode of local invasion. Amoeboid invasion is characterized by rounded cell morphology and
Charlotte M. de Winde, Samantha L. George, Eva Crosas-Molist, Yukti Hari-Gupta, Abbey B. Arp, Agnesska C. Benjamin, Lindsey J. Millward, Spyridon Makris, Alexander Carver, Valerio Imperatore, Víctor G. Martínez, Victoria Sanz-Moreno, Sophie E. Acton   +12 more
doaj   +1 more source

Immune function and dysfunction are determined by lymphoid tissue efficacy

Disease Models & Mechanisms, 2022
Lymphoid tissue returns to a steady state once each immune response is resolved, and although this occurs multiple times throughout life, its structural integrity and functionality remain unaffected. Stromal cells orchestrate cellular interactions within
Spyridon Makris, Charlotte M. de Winde, Harry L. Horsnell, Jesús A. Cantoral-Rebordinos, Rachel E. Finlay, Sophie E. Acton   +5 more
doaj   +1 more source

Macrophage – tumor cell interaction beyond cytokines

Frontiers in Oncology, 2023
Tumor cells communication with tumor associated macrophages is a highly important factor of tumor malignant potential development. For a long time, studies of this interaction were focused on a cytokine- and other soluble factors -mediated processes ...
Olga Kovaleva, Maxim Sorokin, Anastasija Egorova, Anatoly Petrenko, Ksenya Shelekhova, Ksenya Shelekhova, Alexei Gratchev   +6 more
doaj   +1 more source

Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function

Open Biology, 2023
Upon initial immune challenge, dendritic cells (DCs) migrate to lymph nodes and interact with fibroblastic reticular cells (FRCs) via C-type lectin-like receptor 2 (CLEC-2).
Shu En Lim, Megan D. Joseph, Charlotte M. de Winde, Sophie E. Acton, Sabrina Simoncelli   +4 more
doaj   +1 more source

Control of human endometrial stromal cell motility by PDGF-BB, HB-EGF and trophoblast-secreted factors [PDF]

, 2013
Human implantation involves extensive tissue remodeling at the fetal-maternal interface. It is becoming increasingly evident that not only trophoblast, but also decidualizing endometrial stromal cells are inherently motile and invasive, and likely ...
A Brar, A Samalecos, A Stavreus-Evers, AA Brahmbhatt, Ana-Maria Bamberger, Anja Wolf, Annemarie Samalecos, AT Fazleabas, B Cloke, B Gellersen, B Gellersen, BA Lessey, Birgit Gellersen, C Ferretti, C Fischer, C Gaggioli, Charlotte H. E. Weimar, CHE Weimar, CM Boomsma, CP Thomas, D Gentilini, D Gentilini, D Haouzi, DE Clark, EE Sander, ER Norwitz, F Chang, F Llorens, F Lyall, G Gaus, G Teklenburg, G Teklenburg, GE Lash, GE Lash, GJ Burton, H Funayama, H Matsumoto, H Xie, HJ Lim, HJ Yoo, I Ihnatovych, IY Yotova, J Anacker, J Baulida, J Fiedler, JJ Brosens, JJ Brosens, JW Tullai, JX Zhu, K Chobotova, K Kawada, K Red-Horse, K Roepstorff, LA Salamonsen, M Bilban, M Bilban, M Cohen, M Gonzalez, M Knöfler, M Knöfler, M Salker, Maren Schwenke, Martin Knöfler, Meijing Wang, Michelle Kruse, MW Maijenburg, Nick S. Macklon, NJ Hannan, NJ Hannan, P Burke, P Jessmon, P Jessmon, P Kaufmann, Philipp Velicky, R Apps, RE Leach, RE Leach, RE Leach, RJ Petrie, RL Kendall, RN Popovici, S Grewal, S Grewal, SK Mitra, Y Jiang, Y Yamazaki   +85 more
core   +9 more sources

Multitargeting Effects of Calebin A on Malignancy of CRC Cells in Multicellular Tumor Microenvironment

Frontiers in Oncology, 2021
BackgroundTumor microenvironment (TME) provides the essential prerequisite niche for promoting cancer progression and metastasis. Calebin A, a component of Curcuma longa, has long been investigated as a safe multitargeted agent with antitumor and anti ...
Constanze Buhrmann, Constanze Buhrmann, Ajaikumar B. Kunnumakkara, Aviral Kumar, Marek Samec, Peter Kubatka, Bharat B. Aggarwal, Mehdi Shakibaei   +7 more
doaj   +1 more source

Mesenchymal Stromal Cells Support Endometriotic Stromal CellsIn Vitro [PDF]

Stem Cells International, 2018
Endometriosis is an inflammatory disease marked by ectopic growth of endometrial cells. Mesenchymal stromal cells (MSC) have immunosuppressive properties that have been suggested as a treatment for inflammatory diseases. Therefore, the aim herein was to examine effects of allogeneic MSC on endometriosis-derived cellsin vitroas a potential therapy for ...
Fawaz Abomaray, Sebastian Gidlöf, Bartosz Bezubik, Mikael Engman, Cecilia Götherström   +4 more
openaire   +3 more sources