Results 1 to 10 of about 12,161,161 (260)
Mesenchymal Stromal Cells Support Endometriotic Stromal Cells In Vitro [PDF]
Stem Cells International, 2018 Endometriosis is an inflammatory disease marked by ectopic growth of endometrial cells. Mesenchymal stromal cells (MSC) have immunosuppressive properties that have been suggested as a treatment for inflammatory diseases.
Fawaz Abomaray +4 more
doaj +4 more sources
Stromal cells in the tumor microenvironment: accomplices of tumor progression?
Cell Death and Disease, 2023 The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao +9 more
doaj +2 more sources
Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches
Immunity, 2019 &NA; Type 2 lymphocytes promote both physiologic tissue remodeling and allergic pathology, yet their physical tissue niches are poorly described. Here, we used quantitative imaging to define the tissue niches of group 2 innate lymphoid cells (ILC2s ...
Matthew Krummel +2 more
exaly +2 more sources
Mesenchymal stromal cells in the thymus
Inflammation and Regeneration, 2022 The microenvironment of the thymus is composed of a group of stromal cells that include endoderm-derived thymic epithelial cells (TECs) and mesenchymal stromal cells such as fibroblasts and serves as a site for the development of T cells.
Takeshi Nitta
doaj +3 more sources
Stromal Cells in the Tumor Microenvironment.
Advances in Experimental Medicine and Biology, 2018 The tumor microenvironment comprises a mass of heterogeneous cell types, including immune cells, endothelial cells, and fibroblasts, alongside cancer cells.
A. Denton, Edward W. Roberts, D. Fearon
semanticscholar +4 more sources
eLife, 2022 Acute myeloid leukaemia (AML) cells interact and modulate components of their surrounding microenvironment into their own benefit. Stromal cells have been shown to support AML survival and progression through various mechanisms.
Nuria Vilaplana-Lopera +18 more
doaj +1 more source
Challenges and advances in clinical applications of mesenchymal stromal cells
Journal of Hematology & Oncology, 2021 Mesenchymal stromal cells (MSCs), also known as mesenchymal stem cells, have been intensely investigated for clinical applications within the last decades.
Tian Zhou +6 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 Endometriosis is an inflammatory disease that presents with ectopic endometriotic lesions. Reduced immunosurveillance of these lesions has been proposed to be playing a role in the pathology of endometriosis.
Fawaz Abomaray +7 more
doaj +1 more source
Mesenchymal stem/stromal cells in cancer therapy
Journal of Hematology & Oncology, 2021 The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone marrow in 1976, have been identified in nearly all tissues of human body now. The multipotency of MSCs allows them to give rise to osteocytes, chondrocytes, adipocytes,
Tianxia Lan, Min Luo, Xiawei Wei
semanticscholar +1 more source
The Stromal Activity of Mesenchymal Stromal Cells [PDF]
Transfusion Medicine and Hemotherapy, 2008 SUMMARY: The mechanism that regulates self-renewal and differentiation of hematopoietic stem cells (HSC) is a central question in stem cell biology that might ultimately lead to reliable protocols for in vitro expansion of HSC. Cellular fate is governed by cell-cell interaction with the microenvironment in the bone marrow, the stem cell niche ...
Wolfgang, Wagner +2 more
openaire +2 more sources