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Mesenchymal Stromal Cells Support Endometriotic Stromal Cells In Vitro [PDF]
Stem Cells International, 2018 Endometriosis is an inflammatory disease marked by ectopic growth of endometrial cells. Mesenchymal stromal cells (MSC) have immunosuppressive properties that have been suggested as a treatment for inflammatory diseases.
Fawaz Abomaray +4 more
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Mesenchymal stromal cells in the thymus
Inflammation and Regeneration, 2022 The microenvironment of the thymus is composed of a group of stromal cells that include endoderm-derived thymic epithelial cells (TECs) and mesenchymal stromal cells such as fibroblasts and serves as a site for the development of T cells.
Takeshi Nitta
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eLife, 2022 Acute myeloid leukaemia (AML) cells interact and modulate components of their surrounding microenvironment into their own benefit. Stromal cells have been shown to support AML survival and progression through various mechanisms.
Nuria Vilaplana-Lopera +18 more
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Frontiers in Cell and Developmental Biology, 2021 Endometriosis is an inflammatory disease that presents with ectopic endometriotic lesions. Reduced immunosurveillance of these lesions has been proposed to be playing a role in the pathology of endometriosis.
Fawaz Abomaray +7 more
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The Stromal Activity of Mesenchymal Stromal Cells [PDF]
Transfusion Medicine and Hemotherapy, 2008 SUMMARY: The mechanism that regulates self-renewal and differentiation of hematopoietic stem cells (HSC) is a central question in stem cell biology that might ultimately lead to reliable protocols for in vitro expansion of HSC. Cellular fate is governed by cell-cell interaction with the microenvironment in the bone marrow, the stem cell niche ...
Wolfgang, Wagner +2 more
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Stromal cells in the tumor microenvironment: accomplices of tumor progression?
Cell Death and Disease, 2023 The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cells.
Yan Zhao +9 more
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Spontaneous cancer-stromal cell fusion as a mechanism of prostate cancer androgen-independent progression. [PDF]
PLoS ONE, 2012 We have previously shown that human prostate cancer cells are capable of acquiring malignant attributes through interaction with stromal cells in the tumor microenvironment, while the interacting stromal cells can also become affected with both ...
Ruoxiang Wang +7 more
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Umbilical cord mesenchymal stromal cells—from bench to bedside
Frontiers in Cell and Developmental Biology, 2022 In recent years, mesenchymal stromal cells (MSCs) have generated a lot of attention due to their paracrine and immuno-modulatory properties. mesenchymal stromal cells derived from the umbilical cord (UC) are becoming increasingly recognized as having ...
Shashank Chetty +9 more
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Frontiers in Pharmacology, 2023 Myocardial injury is a major pathological factor that causes death in patients with heart diseases. In recent years, mesenchymal stromal cells (MSCs) have been generally used in treating many diseases in animal models and clinical trials.
Wenguang Chang, Peifeng Li
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Frontiers in Immunology, 2021 The balance between the responsiveness of the intestinal immune system and the gut environment is fundamental for the maintenance of intestinal homeostasis, which is required for an adequate recognition of entering antigens.
Marijana Basic +7 more
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