Results 31 to 40 of about 12,161,161 (260)
Haematologica, 2008 Background Mesenchymal stromal cells are multipotent cells considered to be of great promise for use in regenerative medicine. However, the cell dose may be a critical factor in many clinical conditions and the yield resulting from the ex vivo expansion ...
Nadia Sessarego +11 more
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Stromal cell-associated erythropoiesis [PDF]
Blood, 1986 Abstract A novel cover slip-transfer culture system was designed to study the functional roles of stromal cells in hemopoiesis, particularly erythropoiesis. Human bone marrow stromal cell colonies were allowed to develop on small glass cover slips in liquid medium.
S, Tsai, C A, Sieff, D G, Nathan
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Haematologica, 2013 The melanoma cell adhesion molecule defines mesenchymal stromal cells in the human bone marrow that regenerate bone and establish a hematopoietic microenvironment in vivo.
Sabine Stopp +6 more
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Paracrine Mechanisms of Mesenchymal Stromal Cells in Angiogenesis
Stem Cells International, 2020 The role of the mesenchymal stromal cell- (MSC-) derived secretome is becoming increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous tissue repair processes as well as its effective regulation of the immune system,
Selma Maacha +6 more
semanticscholar +1 more source
Marrow stromal stem cells [PDF]
Journal of Clinical Investigation, 2000 Multipotential marrow stromal stem cells were known as early as 1968 (1) through the work of Friedenstein and his coworkers, who established that cells that are adherent, clonogenic, nonphagocytic, and fibroblastic in habit (defined as colony-forming units–fibroblastic; CFU-Fs) can be isolated from the bone marrow stroma of postnatal organisms. CFU-Fs,
BIANCO, Paolo, Pamela Gehron Robey
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Comprehensive Comparison of Amnion Stromal Cells and Chorion Stromal Cells by RNA-Seq [PDF]
International Journal of Molecular Sciences, 2021 Mesenchymal stromal cells derived from the fetal placenta, composed of an amnion membrane, chorion membrane, and umbilical cord, have emerged as promising sources for regenerative medicine. Here, we used next-generation sequencing technology to comprehensively compare amniotic stromal cells (ASCs) with chorionic stromal cells (CSCs) at the molecular ...
Jones, Brielle +8 more
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Haematologica, 2013 Multipotent stromal cells have immunomodulatory capacities and have been used in transplantation and autoimmune diseases. One of the effects of multipotent stromal cells involves the inhibition of dendritic cell differentiation.
Sara M. Melief +3 more
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Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. [PDF]
PLoS ONE, 2015 Fibroblast-like stromal cells modulate cancer cells through secreted factors and adhesion, but those factors are not fully understood. Here, we have identified critical stromal factors that modulate cancer growth positively and negatively.
Manabu Kawada +12 more
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Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance We describe here the most comprehensive analyses of extracellular matrix (ECM) of pancreatic ductal adenocarcinoma (PDAC) yet available, which detected previously unknown molecular changes during PDAC progression in both mouse models and ...
Chenxi Tian +9 more
semanticscholar +1 more source
Frontiers in Hematology, 2023 Prostaglandin E2 (PGE2) signaling through its EP4 receptor regulates hematopoietic stem and progenitor cell (HSPC) functions. Here we generated mouse strains with conditional and inducible deletion of EP4 in stromal cell populations, including ...
Liqiong Liu +5 more
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