Results 11 to 20 of about 404,142 (315)

Can a Conversation Between Mesenchymal Stromal Cells and Macrophages Solve the Crisis in the Inflamed Intestine?

open access: yesFrontiers in Pharmacology, 2018
Inflammatory bowel disease (IBD) is a group of chronic inflammatory conditions of the gastrointestinal tract characterized by an exacerbated mucosal immune response.
Laura Hidalgo-Garcia   +3 more
doaj   +1 more source

Stromal cells

open access: yesFrontiers in Bioscience, 2009
Stromal cells, or mesenchymal stem cells, are adherent clonogenic cells that can form colonies. They are mainly isolated from bone marrow but can also be found in umbilical cord blood, adipose tissues and amniotic fluids. These stem cells are easy to culture in vitro, and can differentiate into osteoblasts, chondrocytes, or adipocytes when stimulated ...
Vayssade, M., Nagel, M.D.
openaire   +3 more sources

Mesenchymal Differentiation and Organ Distribution of Established Human Stromal Cell Lines in NOD/SCID Mice [PDF]

open access: yes, 2001
Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support
Thalmeier, Karin   +5 more
core   +1 more source

Mesenchymal stromal cell therapy for damaged retinal ganglion cells, is gold all that glitters?

open access: yesNeural Regeneration Research, 2019
Mesenchymal stromal cells are an excellent source of stem cells because they are isolated from adult tissues or perinatal derivatives, avoiding the ethical concerns that encumber embryonic stem cells.
Fernando Lucas-Ruiz   +8 more
doaj   +1 more source

Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies

open access: yesFrontiers in Cell and Developmental Biology, 2023
Introduction: The glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab has been licensed for treatment in follicular non-Hodgkin lymphoma and B-CLL following clinical trials demonstrating superior outcomes to standard of care treatment ...
Ester Fagnano   +10 more
doaj   +1 more source

Adipose-derived mesenchymal stromal/stem cells : tissue localization, characterization, and heterogeneity [PDF]

open access: yes, 2012
Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal ...
Helmut Geiger   +3 more
core   +1 more source

Mesenchymal Stromal Cells

open access: yesPostępy Higieny i Medycyny Doświadczalnej, 2014
Mesenchymal stromal cells (MSCs) have been among the most intensively studied cells in recent years. Lack of specific unique markers for these cells makes it difficult to distinguish MSCs from other types of cells, such as fibroblasts or pericytes. MSCs are a mixture of morphologically different cells with expression of various cellular markers, with ...
Stanisław, Szala   +2 more
openaire   +2 more sources

TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]

open access: yes, 2010
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Jones Marius   +30 more
core   +1 more source

Mesenchymal stromal cells and autoimmunity [PDF]

open access: yesInternational Immunology, 2017
Abstract Mesenchymal stromal cells (MSCs) are committed progenitors of mesodermal origin that are found virtually in every organ and exhibit multilineage differentiation into osteocytes, adipocytes and chondrocytes. MSCs also mediate a wide spectrum of immunoregulatory activities that usually dampen innate and adaptive immune responses ...
Lizzia Raffaghello, Vito Pistoia
openaire   +3 more sources

Isolation of human bone marrow stromal cells from bone marrow biopsies for single-cell RNA sequencing

open access: yesSTAR Protocols, 2021
Summary: Bone marrow (BM) mesenchymal stromal cells play an important role in regulating stem cell quiescence and homeostasis; they are also key contributors to various hematological malignancies. However, human bone marrow stromal cells are difficult to
Hélène F.E. Gleitz   +4 more
doaj   +1 more source

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