Development of methods for the in-vitro assessment of the adipogenesis and immunogenicity of human multipotent mesenchymal stromal cells [PDF]
Adult mesenchymal stromal cells (MSCs) have enormous potential in tissue engineering and regenerative medicine applications. MSC have also been reported to be immune-privileged.
Aldridge, Andrew Robert
core +6 more sources
Inflammatory bowel disease (IBD) is a group of chronic inflammatory conditions of the gastrointestinal tract characterized by an exacerbated mucosal immune response.
Laura Hidalgo-Garcia +3 more
doaj +1 more source
Stromal cells, or mesenchymal stem cells, are adherent clonogenic cells that can form colonies. They are mainly isolated from bone marrow but can also be found in umbilical cord blood, adipose tissues and amniotic fluids. These stem cells are easy to culture in vitro, and can differentiate into osteoblasts, chondrocytes, or adipocytes when stimulated ...
Vayssade, M., Nagel, M.D.
openaire +3 more sources
Mesenchymal Differentiation and Organ Distribution of Established Human Stromal Cell Lines in NOD/SCID Mice [PDF]
Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support
Thalmeier, Karin +6 more
core +1 more source
Stromal Cells and Extracellular Vesicles
Stromal cells are stem cells in the bone marrow microenvironment that can ‘talk’ with neighbouring and distant cells within the bone marrow microenvironment.
Kelechi Okeke +2 more
core +1 more source
Mesenchymal stromal cell therapy for damaged retinal ganglion cells, is gold all that glitters?
Mesenchymal stromal cells are an excellent source of stem cells because they are isolated from adult tissues or perinatal derivatives, avoiding the ethical concerns that encumber embryonic stem cells.
Fernando Lucas-Ruiz +8 more
doaj +1 more source
Adipose-derived mesenchymal stromal/stem cells : tissue localization, characterization, and heterogeneity [PDF]
Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal ...
Helmut Geiger +3 more
core +1 more source
Mesenchymal stromal cells (MSCs) have been among the most intensively studied cells in recent years. Lack of specific unique markers for these cells makes it difficult to distinguish MSCs from other types of cells, such as fibroblasts or pericytes. MSCs are a mixture of morphologically different cells with expression of various cellular markers, with ...
Stanisław, Szala +2 more
openaire +2 more sources
TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Jones Marius +30 more
core +1 more source
Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies
Introduction: The glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab has been licensed for treatment in follicular non-Hodgkin lymphoma and B-CLL following clinical trials demonstrating superior outcomes to standard of care treatment ...
Ester Fagnano +10 more
doaj +1 more source

