Results 221 to 230 of about 548,364 (335)

An Organ‐on‐Chip Platform for Strain‐Controlled, Tissue‐Specific Compression of Cartilage and Mineralized Osteochondral Interface to Study Mechanical Overloading in Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi   +10 more
wiley   +1 more source

ARM-X: an adaptable mesenchymal stromal cell-based vaccination platform suitable for solid tumors. [PDF]

open access: yesStem Cell Res Ther
Bikorimana JP   +10 more
europepmc   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah   +9 more
wiley   +1 more source

Modeling mesenchymal stromal cell support to hematopoiesis within a novel 3D artificial marrow organoid system. [PDF]

open access: yesSci Rep
Schell B   +13 more
europepmc   +1 more source

Mechanical Reinforced and Self‐healing Hydrogels: Bioprinted Biomimetic Methacrylated Collagen Peptide‐Xanthan Gum Constructs for Ligament Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Readily UV‐curing and self‐healing methacrylated collagen peptide (COPMA) hydrogels are developed with tunable mechanical properties. As the interpenetrating network between COPMA and xanthan gum (XG), COPMA‐XG bioinks show improved mechanical properties, printability, and stability, compared to COPMA or XG.
Hongjuan Weng   +6 more
wiley   +1 more source

Donor age and breed determine mesenchymal stromal cell characteristics. [PDF]

open access: yesStem Cell Res Ther
Heyman E   +6 more
europepmc   +1 more source

Expression of VLA-4 on thymocytes. Maturation stage-associated transition and its correlation with their capacity to adhere to thymic stromal cells. [PDF]

open access: bronze, 1992
Masumi Sawada   +9 more
openalex   +1 more source

Home - About - Disclaimer - Privacy