Results 241 to 250 of about 11,256,402 (404)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

A molecular systems architecture of the mesenchymal stromal cell microenvironment. [PDF]

Stem Cells
Ayyadurai VAS, Deonikar P, Radhakrishnan V, Keating A.   +3 more
europepmc   +1 more source

200. A Novel Non-Viral Polymer for Plasmid Delivery to Bone Marrow Stromal Cells (BMSC)

, 2006
Başak Açan Clements, Vanessa Incani, Cezary Kucharski, Afsaneh Lavasanifar, Hasan Uludağ   +4 more
openalex   +1 more source

Microencapsulated VEGF gene–modified umbilical cord mesenchymal stromal cells promote the vascularization of tissue-engineered dermis: an experimental study [PDF]

, 2014
Yanfu Han, Ran Tao, Yanqing Han, Tianjun Sun, Jiake Chai, Guang Xu, Jing Liu   +6 more
openalex   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Antibody-conjugated mesenchymal stromal cell drug delivery system for the treatment of autoimmune diseases in mice. [PDF]

Nat Commun
Xie Q, Shen Y, Liang J, Fu C, Du X, Huang S, Song B, Chen L, Wang Y.   +8 more
europepmc   +1 more source

The Paracrine Effect of Hedgehog on Bone Marrow-Derived Stromal Cells Occurs at Later Stages of Pancreatic Tumorigenesis

, 2011
Yoshiaki Sugiyama, Yusuke Mizukami, Toru Kawamoto, Junpei Sasajima, Kazuya Koizumi, Yoshiki Nomura, Kentaro Moriichi, Mikihiro Fujiya, Nabeel Bardeesy, Daniel C. Chung, Yutaka Kohgo   +10 more
openalex   +1 more source

Mesenchymal Stromal Cells

Biology of Blood and Marrow Transplantation, 2007
Horwitz, Edwin M., Andreef, Michael, Frassoni, Francesco   +2 more
openaire   +1 more source

DNA Origami‐Templated Aptamer Chiral Structures Realize Cellular Enantioselectivity

Advanced Materials, EarlyView.
Aptamers displayed on tubular DNA origami nanostructures in defined chiral orientations (left‐ or right‐handed) exhibit enantioselective interactions with cell surface target proteins. While the right‐handed configuration supports only transient binding, the left handedness energetically favors protein dimerization and promotes subsequent ...
Tingjie Song, Abhisek Dwivedy, Dhanush Gandavadi, Gayatri Chandran, Yiquan An, Mengxi Zheng, Xiaojing Wang, Lifeng Zhou, Yang Zhao, Xing Wang   +9 more
wiley   +1 more source

GM-CSF improves the receptivity of thin endometrium by promoting glandular and stromal cell proliferation in mice and humans. [PDF]

Cell Death Discov
Xie J, Xu Q, Fu T, Zhu L, Zhu Q, Wang X, Dong Q, Huang G, Li J, Yang Z, Chen M, Luo X.   +11 more
europepmc   +1 more source