Results 41 to 50 of about 11,256,402 (404)

Molecular characterization of colorectal mucinous adenocarcinoma and adenocarcinoma, not otherwise specified, identified by multiomic data analysis

open access: yesFrontiers in Molecular Biosciences, 2023
Adenocarcinoma not otherwise specified (AC) and mucinous adenocarcinoma (MC) have different biological behaviors and clinical features. We utilized our previous proteomic data and public transcriptome, single-cell transcriptome, and spatial transcriptome
Kailun Xu   +4 more
doaj   +1 more source

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]

open access: yes, 2020
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna   +8 more
core   +2 more sources

Regulation of pancreatic cancer aggressiveness by stromal stiffening [PDF]

open access: yes, 2016
No abstract ...
A Neesse   +13 more
core   +1 more source

Wnt Signaling Inhibits High-Density Cell Sheet Culture Induced Mesenchymal Stromal Cell Aging by Targeting Cell Cycle Inhibitor p27

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Mesenchymal stromal cell senescence and apoptosis have been identified as critical molecular hallmarks in aging. In this study, we used stromal cell sheet culture as an in vitro model to study the progressive changes of cellular senescence, apoptosis and
Ying Xu   +6 more
doaj   +1 more source

Remodeling of Stromal Cells and Immune Landscape in Microenvironment During Tumor Progression

open access: yesFrontiers in Oncology, 2021
The molecular understanding of carcinogenesis and tumor progression rests in intra and inter-tumoral heterogeneity. Solid tumors confined with vast diversity of genetic abnormalities, epigenetic modifications, and environmental cues that differ at each ...
Leena Arora, Durba Pal
doaj   +1 more source

Local nascent protein deposition and remodeling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels

open access: yesNature Materials, 2019
Hydrogels serve as valuable tools for studying cell–extracellular matrix interactions in three-dimensional environments that recapitulate aspects of native extracellular matrix.
Claudia Loebel, R. Mauck, J. Burdick
semanticscholar   +1 more source

Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival

open access: yesFrontiers in Molecular Biosciences, 2022
Regenerative medicine aims to repair degenerate tissue through cell refurbishment with minimally invasive procedures. Adipose tissue (FAT)-derived stem or stromal cells are a convenient autologous choice for many regenerative cell therapy approaches. The
Leon Lufkin   +11 more
doaj   +1 more source

Pre-Clinical Evaluation of Efficacy and Safety of Human Limbus-Derived Stromal/Mesenchymal Stem Cells with and without Alginate Encapsulation for Future Clinical Applications

open access: yesCells, 2023
Corneal opacification or scarring is one of the leading causes of blindness worldwide. Human limbus-derived stromal/mesenchymal stem cells (hLMSCs) have the potential of clearing corneal scarring. In the current preclinical studies, we aimed to determine
Mukesh Damala   +4 more
doaj   +1 more source

Stromal Cell Induction of Regulatory Dendritic Cells [PDF]

open access: yesFrontiers in Immunology, 2012
Dendritic cells (DCs) are specialized antigen presenting cells of bone marrow origin that can exist in tissues in either an immature or mature state. DCs have a myriad of roles in immunity and tolerance induction, but are perhaps best known for their role in the activation and differentiation of naïve T cells at the onset of an acquired immune response.
Owens, Benjamin M. J., Kaye, Paul M.
openaire   +3 more sources

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