Results 111 to 120 of about 2,750 (291)
Advanced Science, EarlyView.Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source
FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model
Advanced Science, EarlyView.FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble +9 more
wiley +1 more source
, 1999 Factors associated with conidial germination and germ tube length of Colletrichum gloeosporioides, a Polystigma rubrum subsp. rubrum stromata mycoparasite, have been studied in vitro. Maximal germination was obtained at 20°C and pH ranging from 6-7.
Stojanović, S. +2 more
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The Stromata vol. 55, no. 1 [PDF]
, 2014 Inside This Issue 2- Genesis 37:1-11 by Tae Kyung Jun 6- I Thessalonians 4:13-18 by Betsy DeVries 15- Cornelius Van Til: The Misunderstood Apologist by Shelby Gemmen 29- Visions of Grace: Sacramental Metaphors in Thomas Aquinas\u27 Summa Theologiae and ...
Calvin Theological Seminary
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, 2011 Hypovirulence in Sclerotinia homoeocarpa is associated with infection by Ophiostoma mitovirus 3a (OMV3a). OMV3a is also present in asymptomatic isolates, with growth and virulence comparable to that of virus-free isolates.
A.M. Orshinsky, G.J. Boland
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Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes
Advanced Science, EarlyView.PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami +15 more
wiley +1 more source
, 1989 Departamento de Protección Vegetal[EN] influence of an isolate of Penicillium frequentans and two of its antibiotics on the mycelium of Monilinia laxa n culture has been studied using light and electron microscopy. Penicillium frequentans and antibiotic
Melgarejo, Paloma +2 more
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Advanced Science, EarlyView.SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley +1 more source
, 2001 In This Issue 4- Lewis’ Imaginative Use of Exhortation: The Significance of C.S. Lewis’ Apologetical Theology for Contemporary Ministry by Jordan J. Ballor 8- Christ on Rood: A poetic look at Christ.
Calvin Theological Seminary
core
Advanced Science, EarlyView.Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu +11 more
wiley +1 more source