Results 131 to 140 of about 2,750 (291)

A Pancreatitis‐Inspired Trypsinogen Nanoplatform Reprograms Tumor‐Associated Macrophages via NF‐κB for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Trypsinogen‐loaded nanoparticles reprogram TAMs via NF‐κB/NLRP3, driving M2→M1 conversion and potent phagocytosis to unleash antitumor immunity. ABSTRACT Although reprogramming tumor‐associated macrophages (TAMs) represents a promising therapeutic strategy, approaches that are both precise and safe remain scarce.
Lei Cao   +7 more
wiley   +1 more source

The Stromata vol. 54, no. 1

open access: yes, 2013
Inside This Issue 4- Editorial by Joshua C. Smith 5- Autumn by Diana Burns 6- Living the Good Life by Matthew Burns 13- Strangers in a Strange Land by Michael Kornelis 10- So, You are a King? by John C.
Calvin Theological Seminary
core  

Los argumentos para la comprensión de Dios en Clemente de Alejandría: Influjos órficos en "Stromata V" [PDF]

open access: yes, 2019
In this article, we examine the incorporation of Orphic texts applied to the understanding of God according to Clement of Alexandria in Stromata V, within the process of receiving Hellenistic culture into the interpretation of the revealed data.
Calabrese, C. (Claudio)
core  

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba   +4 more
wiley   +1 more source

Clinical Significance of PD‐L1 and HLA Expression in Esophageal Squamous Cell Carcinoma in Response to Immunotherapy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study evaluated immune‐related biomarkers in esophageal squamous cell carcinoma treated with immune checkpoint inhibitors after postoperative recurrence. PD‐L1 expression in tumor‐associated macrophages and tumor cells, together with HLA class I downregulation and HLA‐DR expression, were associated with favorable responses to immunotherapy.
Kosuke Kanemitsu   +9 more
wiley   +1 more source

The Stromata vol. 53, no. 2

open access: yes, 2012
Inside This Issue 4- Editorial by John C. Medendorp 5- Richard Bauckham, Jesus and the Eyewitnesses by John C. Medendorp 8- John Dickson, The Best Kept Secret of Christian Mission by Katherine Garvelink Hirschberg 12- Diarmaid MacCullouch, Christianity ...
Calvin Theological Seminary
core  

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

Clement of Alexandria's Stromata in the Early Sixteenth Century

open access: yes, 2023
This article examines the citations from Clement of Alexandria’s Stromata prior to the editio princeps by Piero Vettori (1550) and provides new data on the relationship between that edition and the manuscripts that have preserved this work for future generations.
openaire   +1 more source

The Stromata vol. 51, no. 1

open access: yes, 2010
Inside This Issue 1- The Guys by Walter Miedema 3- A Fool’s Race by Jennifer Holmes 9- Irresponsible Grace by Ruth Lemmen 17- Via Media or Tertium Quid?: A Critical Examination of Meredith G.
Calvin Theological Seminary
core  

Spatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma

open access: yesAdvanced Intelligent Discovery, EarlyView.
Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology.
Shad A. Mohammed   +15 more
wiley   +1 more source

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