Results 51 to 60 of about 1,975 (248)

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Discovery of a novel Keithomyces species isolated from the sclerotia and a new Papiliomyces from Southwest China: Integrated taxonomy based on morphology and phylogeny [PDF]

MycoKeys
Two new Clavicipitaceae species, Papiliomyces huangpingensis sp. nov. and Keithomyces ophiocordycipiticola sp. nov., were described based on integrated morphological features and multi-locus phylogenetic analyses.
Dexiang Tang, Hui Chen, Ou Huang, Ling Tao, Qi-Rui Li, Yao Wang, Xiangchun Sheng   +6 more
doaj   +3 more sources

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Contribution to the knowledge of the genus Neohypodiscus (Ascomycota) in South America: first records of N. cerebrinus and N. rickii from northwestern Argentina

Boletín de la Sociedad Argentina de Botánica
Background and aims: Neohypodiscus was established to replace Hypodiscus, a later homonym of an angiosperm. The genus is restricted to the Americas and is characterized by massive stromata with non-amyloid unitunicate asci and brown septate ascospores ...
Esteban B. Sir, Patricia V. Medina
doaj   +1 more source

Botanophila flies, vectors of Epichloë fungal spores, are infected by Wolbachia

Mycology, 2019
Epichloë fungi are endophytes within grasses that can form stromata on culms of their hosts. Botanophila flies visit the stromata for egg laying and in the process can vector spermatial spores, thereby cross fertilising the fungus.
Lydia Pagel, Thomas Bultman, Karolina Górzyńska, Marlena Lembicz, Adrian Leuchtmann, Anne Sangliana, Nicola Richards   +6 more
doaj   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

Advanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase, Varsha C. Pujari, Akash V. Fulari, Sunil M. Patange, Sean Li, Danyang Wang, Sagar E. Shirsath   +6 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

Advanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu, Qiyu Fang, Jia Yu, Ting Yu, Huashan Shi, Kaiqi Jin, Lei Jiang, Wentian Zhang   +7 more
wiley   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Graminicolous fungi from Poland. I. Fungi on halophyte Puccinellia distans

Acta Mycologica, 2014
The host plant Puccinellia distans was found to be inhabited by the following fungi: Acrospermum graminum, Cladosporium herbarum, Colletotrichum capsici, Dinemasporium slrigosum, Epichloë typhina, Guignardia graminicola, Ophiosphaerella herpotricha ...
Andrzej Chlebicki, Marlena Lembicz
doaj   +1 more source