Results 111 to 120 of about 13,075,262 (257)

pynbody/pynbody: Version 2.0.0-beta.9

open access: yes
<h2>What's Changed</h2> <p>An emergency fix to address a race issue with getting halos on multiple threads at once https://github.com/pynbody/pynbody/pull/813</p> <p><strong>Full Changelog</strong>: https ...
mihaimt   +27 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Transonic Turbulence and Density Fluctuations in the Near-Sun Solar Wind

open access: yesThe Astrophysical Journal Letters
We use in situ measurements from the first 19 encounters of Parker Solar Probe and the most recent five encounters of Solar Orbiter to study the evolution of the turbulent sonic Mach number M _t (the ratio of the amplitude of velocity fluctuations to the
L.-L. Zhao   +4 more
doaj   +1 more source

Phi Beta Kappa, Alpha Chapter Records [PDF]

open access: yes, 1875
Phi Beta Kappa was founded by five students at the College of William and Mary in 1776. This minute book documents the organization in the period 1875-1905.
Phi Beta Kappa   +1 more
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

The intestinal Stenotrophomonas maltophilia ZG-GX enhances the resistance of Spodoptera frugiperda to beta-cypermethrin and decreases the amino acid levels

open access: yesMicrobiology Spectrum
Spodoptera frugiperda is an invasive agricultural pest with a high tolerance for chemical insecticides. An increasing number of studies have reported that intestinal microbes of insects can affect host resistance to insecticides. Therefore, in this study,
Yong Duan   +6 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

LabSid-USP/RUBEM: v0.2.3-beta.2

open access: yes
<h2>What's Changed</h2> <ul> <li>Fix error in the implementation of the Total Discharge equation by @soaressgabriel in https://github.com/LabSid-USP/RUBEM/pull/106</li> </ul> <p><strong>Full Changelog< ...
Daniel Manabe Pasetti   +2 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy