Results 51 to 60 of about 12,543,753 (247)

Plasmid profile of ESBL producing Gram-negative bacteria and correlation with susceptibility to β-lactam drugs

Indian Journal of Pathology and Microbiology, 2010
Background: Members of family Enterobacteriaceae can acquire resistance to extended spectrum beta lactams by a number of mechanisms; most important being the plasmid encoded extended spectrum beta lactamase (ESBL) and AmpC beta lactamase. This study has
Sharma Jyoti, Ray Pallab, Sharma Meera
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Modeling traffic-light systems: A neutrosophic graph approach

Journal of Nigerian Society of Physical Sciences
The coloring of neutrosophic graphs (NGs) is an important concept with extensive real-world applications. This research focuses on chromatic numbers for NGs and their operations.
K Deva, K Siva, Gamachu Adugna Ganati, Walid Abdelfattah, Fikadu Tesgera Tolasa, Naisr Ali, Aseel Smerat, A. Mehmood   +7 more
doaj   +1 more source

Profile of Ectopic Pregnancy at Western Regional Hospital

Journal of College of Medical Sciences-Nepal, 2017
Background & Objective: Ectopic pregnancy (EP) is one of the common life threatening obstetric emergencies which if not recognized and managed on time can be ruptured which could be a cause of death.
Rabi Prasad Regmi, Shyam Sundar Parajuly, Ananda Bahadur Shrestha, Dela Joshi Singh, Sarvesh Gyawali   +4 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Statistics of Feynman amplitudes in ϕ 4-theory

Journal of High Energy Physics, 2023
The amplitude of subdivergence-free logarithmically divergent Feynman graphs in ϕ 4-theory in 4 spacetime dimensions is given by a single number, the Feynman period. We numerically compute the periods of 1.3 million completed graphs, this represents more
Paul-Hermann Balduf
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

La metafora. Testi greci e latini tradotti e commentati da Giulio Guidorizzi e Simone Beta

, 2000
Il volume consiste nello sviluppo e nel completamento di un lavoro pubblicato da Giulio Guidorizzi nel 1984 sotto forma di dispensa universitaria (Testi antichi sulla metafora), che consisteva in un'introduzione sul tropo della metafora nella cultura ...
GUIDORIZZI G., BETA, SIMONE
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source