Results 91 to 100 of about 36,156 (297)

Strong compactness, measurability, and the class of supercompact cardinals [PDF]

open access: yesFundamenta Mathematicae, 2001
In this paper, the author continues the investigation of the possible interplays of supercompactness, strong compactness and measurability. The author shows how to achieve simultaneously the following three properties when designing forcing extensions: (1) preserve the supercompactness of all those supercompact cardinals which are limits of ...
openaire   +2 more sources

THE HALPERN–LÄUCHLI THEOREM AT A MEASURABLE CARDINAL

open access: yes, 2017
Several variants of the Halpern–Läuchli Theorem for trees of uncountable height are investigated. Forκweakly compact, we prove that the various statements are all equivalent, and hence, the strong tree version holds for one tree on any weakly compact ...
NATASHA DOBRINEN, DAN HATHAWAY
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Neurobiological measurements of cardinal utility: Hedonimeters or learning algorithms?

open access: yes, 2002
A neurobiological argument has been used to defend the measurability and interpersonal comparability of cardinal utility. If true, a strong case could be made for the practical relevance of utility-based social welfare functions.
Zizzo, Daniel John
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

An almost strong relation

open access: yes, 2023
Let $\mu$ be a strong limit singular cardinal. We prove that if $2^{\mu} > \mu^+$ then $\binom{\mu^+}{\mu}\to \binom{\tau}{\mu}_{
Villaveces, Andrés, Garti, Shimon
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

معاصر سماجی روئیے اور فرقہ واریت: بابا گرو نانک کی تعلیمات کی روشنی میں تنقیدی جائزہ

open access: yesPakistan Journal of Islamic Research, 2023
Baba Guru Nanak is a renowned social reformist, founder of Sikhism, a great poet, and philosopher of 21st century. His teachings carried the message of universal brotherhood and social revolution.
Faiza Malik, Tahira Basharat
doaj  

Rowbottom-type properties and a cardinal arithmetic

open access: yes, 1986
Assuming Rowbottom-type properties, we estimate the size of certain families of closed disjoint functions. We show that whenever k k is Rowbottom and 2 ω >
Jan Tryba
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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