Results 121 to 130 of about 4,259,138 (261)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

On the strong uniform consistency of a new kernel density estimator

open access: yes
kernel estimator, strong uniform consistency, sample moments,
R. Theodorescu, B. Abdous
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Strong Consistency of Regression Quantiles and Related Empirical Processes

open access: yes, 1986
The strong consistency of regression quantile statistics (Koenker and Bassett [4]) in linear models with iid errors is established. Mild regularity conditions on the regression design sequence and the error distribution are required.
Gilbert W. Bassett, Roger W. Koenker
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Strong universal consistency of smooth kernel regression estimates

open access: yes
Nonparametric regression estimation, kernel estimate of Nadaraya and Watson, square integrability, strong and weak universal consistency, Efron-Stein inequality, covering, Tauberian theorem,
Harro Walk
core   +1 more source

Consistency of personality traits and verbal behaviour in leaderless small group discussion [PDF]

open access: yes, 1990
The research was concerned with consistency between three types of trait interaction and verbal behaviour in small student discussion groups. Hypotheses based on trait interactions of varying saliency were tested against samples of verbal behaviour ...
Halpin, Nicholas Richard, Halpin, N.R
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Strong consistency of minimum contrast estimators with applications [PDF]

open access: yes, 2003
We prove a strong consistency result for minimum contrast estimators for general regression problems with independent errors using technically transparent proofs.
Bose, Arup, Sengupta, Debapriya
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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