Results 131 to 140 of about 4,259,138 (261)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Strong consistency of least squares estimates in multiple regression II

open access: yes
The strong consistency of least squares estimates in multiple regression models is established under minimal assumptions on the design and weak dependence and moment restrictions on the errors.Multiple regression strong consistency martingale difference ...
Robbins, Herbert, Lai, T. L., Wei, C. Z.
core  

On the Strong Consistency of Approximate Maximum Likelihood Estimators [PDF]

open access: yes, 1969
1 online resource (PDF, 36 pages)Perlman, Michael D.. (1969). On the Strong Consistency of Approximate Maximum Likelihood Estimators.
Perlman, Michael D.
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The strong consistency of M-estimators in linear models

open access: yes
The strong consistency of M-estimators in linear models is considered. Under some conditions on the ratios of maximum and minimum eigenvalues of the information matrices the desired result is established.Information matrix M-estimators scale equivariance
Cheng, Ching-Shui, Li, Ker-Chau
core  

Evaluation of Strong Consistency Web Caching Techniques

open access: yes, 2002
The growth of the World Wide Web (WWW or Web) and its increasing use in all types of business have created bottlenecks that lead to high network and server overload and, eventually, high client latency.
L. Y. Cao, M. T. Özsu
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Strong Universal Pointwise Consistency of Some Regression Function Estimates

open access: yes
The strong universal pointwise consistency of some modified versions of the standard regression function estimates of partitioning, kernel, and nearest neighbor type is shown.nonparametric regression estimation strong universal pointwise consistency ...
Algoet, Paul, Györfi, László
core  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

The L1 strong consistency of ARCH innovation density estimator

open access: yes
In this paper we consider the global property for the innovation density estimator in ARCH time series. For the kernel innovation density estimator based on residuals, we obtain its strong consistency under L1-norm.ARCH-time series Kernel density ...
Wen, Miin-Jye, Cheng, Fuxia
core  

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