Strong Consistency of a Nonparametric Estimator of the Survival Function with Doubly Censored Data [PDF]
Myron Chang, Grace L. Yang
openalex +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
OCDBMamba: A Robust and Efficient Road Pothole Detection Framework with Omnidirectional Context and Consensus-Based Boundary Modeling. [PDF]
Ling F, Lin Y, Mao W, Tang L.
europepmc +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Validity and reliability of the French version of the quick-FAAM (Q-FAAM-F) among patients undergoing anatomic ankle ligament reconstruction. [PDF]
Saliba I +8 more
europepmc +1 more source
Weak and strong consistency of the least squares estimators in regression models [PDF]
Hilmar Drygas
openalex +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Optimizing regional innovation ecosystems through actor-environment coevolution: A dynamic configurational analysis from a CAS perspective. [PDF]
Pang H, Jiang Y, Wu L, Wang L.
europepmc +1 more source

