Results 71 to 80 of about 249,164 (350)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

A Selection of important strong motion earthquake records [PDF]

open access: yes, 1980
This report is a condensed collection of 45 strong and/or historically important earthquake-generated ground and building motions. These data are presented as accelerogram and integrated velocity and displacement time histories.
Housner, George W.   +2 more
core  

Seismic structure-soil-structure interaction between pairs of adjacent building structures [PDF]

open access: yes, 2015
Structure–soil–structure interaction between adjacent structures, which may occur in densely populated urban areas, has received little attention compared to the soil–structure interaction of single isolated structures.
Bertalot D.   +8 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

High‐Frequency Ground Motions of Earthquakes Correlate With Fault Network Complexity

open access: yesGeophysical Research Letters
Understanding the generation of damaging, high‐frequency ground motions during earthquakes is essential both for fundamental science and for effective hazard preparation.
Avigyan Chatterjee   +4 more
doaj   +1 more source

Effect of strong ground motion duration on the expected peak values of floor response spectra in elastic buildings

open access: yesJapan Architectural Review, 2019
Nonstructural components (eg, suspended ceilings, equipment, and piping systems) resonate with buildings and could suffer severe damage during strong earthquakes.
Kensaku Kaneko
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Slip history of the 2003 San Simeon earthquake constrained by combining 1-Hz GPS, strong motion, and teleseismic data [PDF]

open access: yes, 2004
The slip history of the 2003 San Simeon earthquake is constrained by combining strong motion and teleseismic data, along with GPS static offsets and 1-Hz GPS observations.
Choi, Kyuhong   +4 more
core   +2 more sources

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Surface Level Synthetic Ground Motions for M7.6 2001 Gujarat Earthquake

open access: yesGeosciences, 2018
The 2001 Gujarat earthquake was one of the most destructive intraplate earthquakes ever recorded. It had a moment magnitude of M w 7.6 and had a maximum felt intensity of X on the Modified Mercalli Intensity scale.
Jayaprakash Vemuri   +2 more
doaj   +1 more source

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