Results 41 to 50 of about 665,867 (231)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

Gradient-Based Assessment of Habitat Quality for Spectral Ecosystem Monitoring

open access: yesRemote Sensing, 2015
The monitoring of ecosystems alterations has become a crucial task in order to develop valuable habitats for rare and threatened species. The information extracted from hyperspectral remote sensing data enables the generation of highly spatially resolved
Carsten Neumann   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cartan-Weyl 3-algebras and the BLG Theory II: Strong-Semisimplicity and Generalized Cartan-Weyl 3-algebras

open access: yes, 2010
One of the most important questions in the Bagger-Lambert-Gustavsson (BLG) theory of multiple M2-branes is the choice of the Lie 3-algebra. The Lie 3-algebra should be chosen such that the corresponding BLG model is unitary and admits fuzzy 3-sphere as a
Chu, Chong-Sun
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Geometry-informed modeling and evaluation of coverage resilience in complex communication networks

open access: yesApplied Network Science
The development of 5 G technology drives economic and societal advancement. However, the expanding scale and increasing topological complexity of communication networks pose challenges for modeling higher-order coverage dependencies and assessing network
Bingchen Dong, Zhenglin Liang
doaj   +1 more source

Topological study of persistent homology on complicated force chain network evolution in granular media

open access: yes工程科学学报, 2023
The force chain network is a crucial basis for characterizing the essential features of granular media microscopic mechanics and for studying the mechanical behavior of their macroscopic structures.
Jin-an WANG, Liu YANG, Fei LI
doaj   +1 more source

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