Results 111 to 120 of about 1,913,798 (294)

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

A New Dynamic Building Health Monitoring Method Based on the Hilbert-Huang Transform

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2014
The theoretical solution for a Multiple-Degree-Of-Freedom (MDOF) structure is composed of a combination of several individual modes. When we demonstrate the actual response directly on the time-frequency spectrum, the energy distribution is usually ...
Sheng-Chung Su   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Review of source models for reproducing and predicting strong motions by empirical Green's function method

open access: yesJapan Architectural Review
Short‐period ground motions from earthquakes are calculated by semiempirical methods such as the empirical Green's function method or the stochastic Green's function method.
Kazuo Dan
doaj   +1 more source

Strong Ground Motions Generated by the February 11, 2014 Tatunshan Earthquake in the Taipei Metropolitan Area

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2014
Strong-motion seismograms from the 11 February, 2014 Tatunshan earthquake were recorded at stations around the source area. These recordings were used to analyze the strong-motion characteristics in the area.
Kou-Cheng Chen   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Probabilistic Seismic Hazard Assessment for the North China Plain Earthquake Belt: Sensitivity of Seismic Source Models and Ground Motion Prediction Equations

open access: yesInternational Journal of Disaster Risk Science
In this study, a multi-source data fusion method was proposed for the development of a Hybrid seismic hazard model (HSHM) in China by using publicly available data of the 5th Seismic Ground Motion Parameter Zoning Map (NSGM) and historical seismic ...
Jian Ma   +6 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

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