Results 181 to 190 of about 1,185,468 (303)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Young Consumers' Preferences for Nonalcoholic Beers: The Impact of Sensory Perception and Label Information. [PDF]

Int J Food Sci
Klensporf-Pawlik D, Klimczak I, Rybicka I, Gliszczyńska-Świgło A.   +3 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Lucigenin: a strongly oxidizing dicationic photocatalyst for the direct azolation of arenes. [PDF]

Chem Sci
Matei A, Roure B, Chen X, Beil SB, Feringa BL.   +4 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

A Statistical Thinking Approach to Kansei Engineering for Product Innovation

, 2008
With a strong competition and a strong consumer awareness of quality, manufacturers have to look hard at how to satisfy needs and expectations of potential new consumers. The only acceptable level of quality is total. In addition to the functional needs,
Tarantino, Pietro
core  

Bioactive Potential of Post-Distillation Residue of <i>Clinopodium albanicum</i> (Griseb. ex K. Malý) Melnikov: Phytochemical Profiling, Antioxidant and Antimicrobial Activities with Molecular Docking Insights. [PDF]

Plants (Basel)
Stojković D, Božunović J, Filipović B, Bolevich S, Premović Valente N, Ivanov M, Rajaković M, Zengin G, Uba AI, Bolevich S, Gašić U, Soković M.   +11 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Identification of HOTf-Driven Brønsted Acid Catalysis in the AuCl₃/AgOTf System for the Hydroalkylation of Styrene. [PDF]

Inorg Chem
Mahdian A, Nikonovich T, Kaabel S, Laasonen K, Farshadfar K.   +4 more
europepmc   +1 more source