Results 101 to 110 of about 73,445 (249)

Photometric Redshift Forecast for the 7-Dimensional Sky Survey

open access: yesThe Astrophysical Journal
We investigate the expected accuracy of redshifts that can be obtained using low-resolution spectroscopic (medium-band) data from the 7-Dimensional Sky Survey (7DS). By leveraging 40 densely sampled filters with widths of FWHM = 25 nm, we create 7DS mock
Eunhee Ko   +5 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

open access: yesFEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Some resolving parameters with the minimum size for two specific graphs [PDF]

open access: yes
A resolving set for a graph $G$ is a set of vertices $Q = \{q_1, ..., q_k\}$ such that, for all $p\in V(G)$ the $k$-tuple $(d(p, q_1), ..., d(p, q_k ))$ uniquely determines $p$, where $d(p, q_i)$ is considered as the minimum length of a shortest path ...
Alikhani, Saeid, Zafari, Ali
core   +1 more source

Edge-disjoint cycles with the same vertex set [PDF]

open access: yes
In 1975, Erd\H{o}s asked for the maximum number of edges that an $n$-vertex graph can have if it does not contain two edge-disjoint cycles on the same vertex set. It is known that Tur\'an-type results can be used to prove an upper bound of $n^{3/2+o(1)}$.
Methuku, Abhishek   +3 more
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

An Improved PSO-Based Approach for Automated Form-Finding of Cable–Truss Structures

open access: yesBuildings
Determining the compatible prestress and geometry under self-weight constitutes a key challenge in the form-finding of cable–truss structures. To overcome the limitations of experience-dependent trial methods and enhance computational efficiency, this ...
Zhenhua Wang   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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