Results 51 to 60 of about 604,199 (244)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Symmetry breaking in tournaments [PDF]
, 2010 We provide upper bounds for the determining number and the metric dimension of tournaments. A set of vertices S is a determining set for a tournament T if every nontrivial automorphism of T moves at least one vertex of S, while S is a resolving set for T
Lozano Bojados, Antoni
core +1 more source
Missing Stellar Mass in SED Fitting: Spatially Unresolved Photometry can Underestimate Galaxy Masses [PDF]
, 2015 We fit model spectral energy distributions to each pixel in 67 nearby (=0.0057) galaxies using broadband photometry from the Sloan Digital Sky Survey and GALEX.
Sawicki, Marcin, Sorba, Robert
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Host Lipid Mediators in Leprosy: The Hypothesized Contributions to Pathogenesis
Frontiers in Immunology, 2018 The spectrum of clinical forms observed in leprosy and its pathogenesis are dictated by the host’s immune response against Mycobacterium leprae, the etiological agent of leprosy.
Carlos A. M. Silva, John T. Belisle
doaj +1 more source
, 2016 In this work, we revisit Auslander-Buchweitz Approximation Theory and find some relations with cotorsion pairs and model category structures. From the notions of relatives generators and cogenerators in Approximation Theory, we introduce the concept of ...
Becerril, Víctor +3 more
core +1 more source