Results 51 to 60 of about 73,445 (249)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Equilibration of the Antarctic Circumpolar Current by standing meanders [PDF]

open access: yes, 2014
The insensitivity of the Antarctic Circumpolar Current (ACC)’s prominent isopycnal slope to changes in wind stress is thought to stem from the action of mesoscale eddies that counterbalance the wind-driven Ekman overturning—a framework verified in ...
Naveira Garabato, Alberto C.   +1 more
core   +1 more source

Using the Normalization Process Theory to qualitatively explore sense-making in implementation of the Enhanced Recovery After Surgery programme: "It's not rocket science". [PDF]

open access: yesPLoS ONE, 2018
The Enhanced Recovery After Surgery programme (ERAS) is an approach to the perioperative care of patients encompassing multiple interventions and involving a wide range of different actors. It can thus be defined as a complex intervention.
Eileen Sutton   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Guiding Corpus-based Set Expansion by Auxiliary Sets Generation and Co-Expansion [PDF]

open access: yes, 2020
Given a small set of seed entities (e.g., "USA", "Russia"), corpus-based set expansion is to induce an extensive set of entities which share the same semantic class (Country in this example) from a given corpus.
Jiaming Shen   +11 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On the impossibility of representing infinite utility streams [PDF]

open access: yes, 2007
We show that, independently of the topology chosen on the set of all infinity utility streams, there is no Social Welfare Function preserving the von Weizsäcker’s overtaking criterion.
Núñez Sanz, Carmelo   +5 more
core  

Generalized time-invariant overtaking [PDF]

open access: yes
We present a new version of the overtaking criterion, which we call generalized time-invariant overtaking. The generalized time-invariant overtaking criterion (on the space of infinite utility streams) is defined by extending proliferating sequences of ...
Kuntal Banerjee   +2 more
core   +9 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Rodent models for resolving extremes of exercise and health [PDF]

open access: yes, 2016
The extremes of exercise capacity and health are considered a complex interplay between genes and the environment. In general, the study of animal models has proven critical for deep mechanistic exploration that provides guidance for focused and ...
Koch, Lauren G.   +7 more
core   +1 more source

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