Results 71 to 80 of about 604,199 (244)

Probing higher order correlations of the photon field with photon number resolving avalanche photodiodes

, 2011
We demonstrate the use of two high speed avalanche photodiodes in exploring higher order photon correlations. By employing the photon number resolving capability of the photodiodes the response to higher order photon coincidences can be measured.
,, Dynes, JF, Sharpe, AW, Shields, AJ, Thomas, O, Yuan, ZL   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Synthesising, using, and correcting for telluric features in high-resolution astronomical spectra

, 2010
We present a technique to synthesise telluric absorption and emission features both for in-situ wavelength calibration and for their removal from astronomical spectra. While the presented technique is applicable for a wide variety of optical and infrared
A. Seifahrt, Abrams, Bailey, Brault, Brown, Clough, Clough, Clough, Dlugokencky, Figueira, G. Zängl, Griffin, H. U. Käufl, Hase, Horne, J. L. Bean, Jacquinet-Husson, Jacquinet-Husson, Kenworthy, Kerber, Käufl, Käufl, Käufl, Lallement, M. J. Richter, Miller, Niro, R. Siebenmorgen, Rothman, Rothman, Rousselot, Rucinski, Scott, Scott, Seifahrt, Tashkun, Udem, Vacca, Villanueva, Widemann, Zängl, Zängl   +41 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Capability of the building-resolving PALM model system to capture micrometeorological characteristics of an urban environment in Vienna, Austria

City and Environment Interactions
Understanding and evaluating possible changes in thermal conditions of urban settlements are crucial for risk assessment, adaptation to climate change and sustainable urban development.
Brigitta Hollósi, Maja Žuvela-Aloise, Anton Neureiter, Melina Frießenbichler, Peter Auferbauer, Jürgen Feigl, Claudia Hahn, Thomas Kolejka   +7 more
doaj   +1 more source

Timing of early laparoscopic cholecystectomy for acute calculous cholecystitis revised: Protocol of a systematic review and meta-analysis of results

World Journal of Emergency Surgery, 2020
Background Early laparoscopic cholecystectomy has been adopted as the treatment of choice for acute cholecystitis due to a shorter hospital length of stay and no increased morbidity when compared to delayed cholecystectomy.
Giuseppe Borzellino, Safi Khuri, Michele Pisano, Subhi Mansour, Niccolò Allievi, Luca Ansaloni, Yoram Kluger   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

From Sparse to Refined Samples: Iterative Enhancement-Based PDLCM for Multi-Annual 10 m Rice Mapping in the Middle-Lower Yangtze

Remote Sensing
Accurate mapping of rice cultivation is vital for ensuring food security, reducing greenhouse gas emissions, and achieving sustainable development goals.
Lingbo Yang, Jiancong Dong, Cong Xu, Jingfeng Huang, Yichen Wang, Huiqin Ma, Zhongxin Chen, Limin Wang, Jingcheng Zhang   +8 more
doaj   +1 more source

The XDSPRES CL-based package for reducing OSIRIS cross-dispersed spectra

, 2011
We present a description of the CL-based package XDSPRES, which aims at being a complete reducing facility for cross-dispersed spectra taken with the Ohio State Infrared Imager/Spectrometer, as installed at the SOAR telescope.
Daniel Ruschel-Dutra, Jorge Ricardo Ducati, Miriani Pastoriza, Moreno V., Oliva E., Rogério Riffel, Rossi C., Tody D.   +7 more
core   +1 more source