Results 161 to 170 of about 6,213,692 (298)

Deep-ultraviolet chiral interband plasmonics in silicon nanohelices. [PDF]

open access: yesMicrosyst Nanoeng
Kim J   +6 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Stability of Leray weak solutions to 3D Navier-Stokes equations

open access: yesElectronic Journal of Differential Equations
In this article, we show that if the Leray weak solution $u$ of the three-dimensional Navier-Stokes system satisfies $$ \nabla u\in L^p(0,\infty;\dot B^0_{q,\infty}(\mathbb{R}^3)),\quad \frac{2}{p}+\frac{3}{q} =2,\quad \frac{3}{2}
Zujin Zhang, Weijun Yuan, Zhengan Yao
doaj  

Physicochemical Characterization of Choline Amino Acid Protic Ionic Liquids as Sustainable Lubricant Candidates. [PDF]

open access: yesACS Omega
Kiboi DK   +6 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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