Results 131 to 140 of about 430,778 (289)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Potter Cove's Heavyweights: Estimation of Species' Interaction Strength of an Antarctic Food Web

Ecology and Evolution
In the West Antarctic Peninsula, global warming has led to severe alterations in community composition, species distribution, and abundance over the last decades.
Iara Diamela Rodriguez, Leonardo Ariel Saravia   +1 more
doaj   +1 more source

High Stability and Low Power Nanometric Bio-Objects Trapping through Dielectric–Plasmonic Hybrid Nanobowtie

Biosensors
Micro and nano-scale manipulation of living matter is crucial in biomedical applications for diagnostics and pharmaceuticals, facilitating disease study, drug assessment, and biomarker identification.
Paola Colapietro, Giuseppe Brunetti, Annarita di Toma, Francesco Ferrara, Maria Serena Chiriacò, Caterina Ciminelli   +5 more
doaj   +1 more source

Computation of Optimal Linear Strong Stability Preserving Methods Via Adaptive Spectral Transformations of Poisson–Charlier Measures [PDF]

, 2021
Rachid Ait‐Haddou
openalex   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Research on anti-rollover active control of sports utility vehicle with time-delay compensation function.

PLoS ONE
The global incidence of traffic accidents caused by vehicle rollovers has exhibited a persistent upward trajectory in recent years. This paper proposes a novel rollover prevention control method incorporating time-delay compensation to address inherent ...
Dongtao Wang, Yifan Hu, Xuan Liu, Yanjian Shen, Rong Wang   +4 more
doaj   +1 more source

Enhancing Energy Efficiency in Methanol-to-DME Conversion through Process Modification and Heat Integration

Journal of Chemical Engineering Research Progress
Enhancing energy efficiency in dimethyl ether (DME) production is critical for reducing utility consumption and improving process sustainability. This study investigates the impact of targeted modifications to the methanol dehydration system on thermal ...
Salma Salsabila, Meirisa Ayu Saputri, Jorsch Pieter Benhard Sirait, Samuel Kurniawan, Sera Amelia, Alvin Ananta Putra   +5 more
doaj   +1 more source

Modeling Three‐Dimensional Wave Propagation in Anelastic Models With Surface Topography by the Optimal Strong Stability Preserving Runge‐Kutta Method [PDF]

, 2018
Nian Wang, Jiahang Li, Dmitry Borisov, Hom Nath Gharti, Yang Shen, Wei Zhang, Brian Savage   +6 more
openalex   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source