Results 91 to 100 of about 8,926,578 (308)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

NUMERICAL STUDY OF THE INTERFACE TRACKING WITH STRONG SHOCK

Jixie qiangdu, 2016
when the material interface received strong impact,the large gradient zone or mutations of the pressure and velocity will appear on both sides,and in this case,the numerical simulation has become extremely difficult.
ZHANG XuMei, JIANG ZhiGang, ZHANG Liang, WEI ShaoHua   +3 more
doaj  

Psychological mechanisms of multiple object tracking

Экспериментальная психология
Context and relevance. The multiple object tracking task is widely used to evaluate professional abilities. In this regard, it is important to understand the underlying processes, as well as the factors contributing to interindividual ...
M.M. Tcepelevich
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

How strong are the Southern Hemisphere storm tracks?

Geophysical Research Letters, 2009
The real strength of the Southern Hemisphere (SH) storm tracks is poorly known, as the NCEP‐NCAR and ECMWF reanalyses differ significantly in this measure. In this work, the COSMIC GPS radio occultation dataset is used to investigate this issue. The ratio of the strength of the SH storm tracks to that in the Northern Hemisphere (NH) based on the COSMIC
Yanjuan Guo, Edmund K. M. Chang, Stephen S. Leroy   +2 more
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Cognitive-feedback training of hand function in patients after stroke

Zdravniški Vestnik, 2005
Background: Several investigators have shown beneficial effects of cognitive feedback training on the rehabilitation progress of stroke patients. The repetition of different visually guided motor tasks can initiate the relearning process inside the ...
Gregorij Kurillo, Nika Goljar, Tadej Bajd   +2 more
doaj  

A Strong Maneuvering Target-Tracking Filtering Based on Intelligent Algorithm

International Journal of Aerospace Engineering
In this paper, a variable-structure multimodel (VSMM) filtering algorithm based on the long short-term memory (LSTM) regression-deep Q network (L-DQN) is proposed to accurately track strong maneuvering targets.
Jing Li, Xinru Liang, Shengzhi Yuan, Haiyan Li, Changsheng Gao   +4 more
doaj   +1 more source