Results 61 to 70 of about 286,497 (273)

Roughness Evaluation of Burnished Topography with a Precise Definition of the S-L Surface

Applied Sciences, 2022
Studies of surface topography including processes of measurement and data analysis have an influence on the description of machined parts with their tribological performance.
Przemysław Podulka
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The lower bound for number of hexagons in strongly regular graphs with parameters $\lambda=1$ and $\mu=2$ [PDF]

E-Journal of Analysis and Applied Mathematics
The existence of $srg(99,14,1,2)$ has been a question of interest for several decades to the moment. In this paper, we consider the structural properties in general for the family of strongly regular graphs with parameters $\lambda =1$ and $\mu =2$.
Reimbay Reimbayev
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

GRAPHS \(\Gamma\) OF DIAMETER 4 FOR WHICH \(\Gamma_{3,4}\) IS A STRONGLY REGULAR GRAPH WITH \(\mu=4,6\)

Ural Mathematical Journal
We consider antipodal graphs \(\Gamma\) of diameter 4 for which  \(\Gamma_{1,2}\) is a strongly regular graph. A.A. Makhnev and D.V. Paduchikh noticed that, in this case, \(\Delta=\Gamma_{3,4}\) is a strongly regular graph without triangles.
Alexander A. Makhnev, Mikhail P. Golubyatnikov, Konstantin S. Efimov   +2 more
doaj   +1 more source

Two Classes of Linear Codes From Weil Sums

IEEE Access, 2020
In this article, we consider two classes of $p$ -ary linear codes. This article is a generalization of the recent construction methods given by Jian, Lin and Feng (2019).
Hong Lu, Shudi Yang
doaj   +1 more source

Another construction of edge-regular graphs with regular cliques

, 2018
We exhibit a new construction of edge-regular graphs with regular cliques that are not strongly regular. The infinite family of graphs resulting from this construction includes an edge-regular graph with parameters $(24,8,2)$.
Greaves, Gary R. W., Koolen, J. H.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Distance-Regular Graphs with Strongly Regular Subconstituents [PDF]

Journal of Algebraic Combinatorics, 1997
The main result of the article is a theorem about distance-regular graphs of diameter \(d\geq 3\) with all subconstituents being strongly regular graphs. The author shows that these are precisely the Taylor graphs \((d=3\) and \(|\Gamma_3 (u) |=1)\) or graphs with \(a_1= 0\), \(a_i\leq 1\) for \(2\leq i\leq d\).
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source