Results 111 to 120 of about 105,061,129 (288)

Strongly regular graphs induced by polarities of symmetric designs [PDF]

open access: yes
Graphs ...
Higman, D.G.   +2 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Differentiating healthy orthorexia from orthorexia nervosa: sociodemographic, psychological and dietary characteristics in a French sample

open access: yesPublic Health Nutrition
Objective: Orthorexia has been widely studied, but recently, a new conceptualisation was proposed to distinguish its healthy characteristics from its pathological ones.
Eva Hanras   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Strongly regular graphs

open access: yes, 2017
Tema diplomskog rada su jako regularni grafovi. Kako bismo bolje razumijeli sve pojmove diplomski rad podijeljen je na dva dijela. U prvom dijelu koji nam je potreban za lakim razumijevanjem jako regularnih grafova prvo se upoznajemo s teorijom grafova ...
Lukić, Petra
core   +2 more sources

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Almost Strongly Regular Graphs [PDF]

open access: yes
We investigate what we call (δ, )-almost strongly regular graphs with parameters (n,k,λ,µ). In particular, we generalize some well known results and bounds on the parameters of strongly regular graphs from Bose and Dowling (1963) and Babai (1980, 2014 ...
Gomez, Josias
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

On strongly n-regular and strongly regular rings

open access: yes, 2000
Let R be an associative ring with identity 1 (not equal to) 0. An element x E R is said to be right (or left) regular if there exists yin R such that x² y = x (or y.x² = x). If x is both left and right regular, then it is said to be strongly regular. The
Chen, Huey Voon
core  

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