Results 91 to 100 of about 1,121,911 (262)

Physical Exercise Affects Adipose Tissue Profile and Prevents Arterial Thrombosis in BDNF Val66Met Mice

open access: yesCells, 2019
Adipose tissue accumulation is an independent and modifiable risk factor for cardiovascular disease (CVD). The recent CVD European Guidelines strongly recommend regular physical exercise (PE) as a management strategy for prevention and treatment of CVD ...
Leonardo Sandrini   +7 more
doaj   +1 more source

Selenium deficiency is linearly associated with hypoglycemia in healthy adults

open access: yesRedox Biology, 2020
Objective: The trace element selenium (Se) is needed for regular biosynthesis of selenoproteins, which contribute to antioxidative defense systems and affect redox-regulated signaling.
Yue Wang   +6 more
doaj   +1 more source

A generalized Ramanujan-Nagell equation related to certain strongly regular graphs

open access: yesIntegers : Electronic Journal of Combinatorial Number Theory, 2014
Summary: A quadratic-exponential Diophantine equation in 4 variables, describing certain strongly regular graphs, is completely solved. Along the way we encounter different types of generalized Ramanujan-Nagell equations whose complete solution can be found in the literature, and we come across a problem on the order of the prime ideal above 2 in the ...
openaire   +3 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Equivalent Standard Forms of a Class of Tropical Matrices and Centralizer Groups

open access: yesMathematics
In this paper, the equivalent standard forms of tropical idempotent strongly definite matrices are introduced. In particular, the observation of the equivalent standard forms of tropical idempotent normal matrices is given.
Yanliang Cheng
doaj   +1 more source

Viscosity Methods of Asymptotically Pseudocontractive and Asymptotically Nonexpansive Mappings for Variational Inequalities

open access: yesAbstract and Applied Analysis, 2012
Let {𝑡𝑛}⊂(0,1) be such that 𝑡𝑛→1 as 𝑛→∞, let 𝛼 and 𝛽 be two positive numbers such that 𝛼+𝛽=1, and let 𝑓 be a contraction. If 𝑇 be a continuous asymptotically pseudocontractive self-mapping of a nonempty bounded closed convex subset 𝐾 of a real reflexive ...
Xionghua Wu   +3 more
doaj   +1 more source

Serum visfatin in chronic renal failure patients on maintenance hemodialysis: A correlation study

open access: yesThe Egyptian Journal of Internal Medicine, 2013
Background and aim of work Endothelial dysfunction, atherosclerosis, and cardiovascular disease are strongly linked to chronic kidney disease. It has been hypothesized that visfatin may play an important role in uremia-related atherosclerosis and the ...
Abdel Wahab M Lotfy   +3 more
doaj   +1 more source

Cyclotomy, difference sets, sequences with low correlation, strongly regular graphs, and related geometric substructures

open access: yes, 2018
29 pages. To appear in the Proceedings of the Workshop "Pseudorandomness and Finite Fields" at RICAM, Linz, Austria, Oct.
Momihara, Koji, Wang, Qi, Xiang, Qing
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy