Results 71 to 80 of about 1,121,911 (262)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Arsenic exposure in Indo Gangetic plains of Bihar causing increased cancer risk
Scientific Reports, 2021 Reportedly, 300 million people worldwide are affected by the consumption of arsenic contaminated groundwater. India prominently figures amongst them and the state of Bihar has shown an upsurge in cases affected by arsenic poisoning.
Arun Kumar +14 more
doaj +1 more source
On Strongly Regular Relation of Canonical Hypergroup
Al-Mukhtar Journal of Basic SciencesBurris and Sankappanavar established connection between congruence on group G (ring R) and normul subgroup of G (ideal of ring R). In this paper by the same manner, the connection between strongly regular relation defined on canonical hypergroup and normal subcanonical hypergroup of canonical hypergroup is established.
Yasser A. AbouElwan, Maher. A. Alderawe
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
مجلة ابحاث كلية التربية الاساسيةIn our study we examine definition of strongly γ -regular rings and associates, investigate interplay between strongly γ - regular rings and other reduced rings. We also study GP – injective modules, and discuss its relation with strongly
Luma Ahmed Khaleel, Beyda S. Abdullah
doaj +1 more source
Transitivity of the εm-relation on (m-idempotent) hyperrings
Open Mathematics, 2018 On a general hyperring, there is a fundamental relation, denoted γ*, such that the quotient set is a classical ring. In a previous paper, the authors defined the relation εm on general hyperrings, proving that its transitive closure εm∗$\begin{array}{} \
Norouzi Morteza, Cristea Irina
doaj +1 more source
The architecture of partisan debates: The online controversy on the no-deal Brexit.
PLoS ONE, 2022 We propose a framework to analyse partisan debates that involves extracting, classifying and exploring the latent argumentation structure and dynamics of online societal controversies.
Carlo Romano Marcello Alessandro Santagiustina +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Space time manifolds and contact structures
International Journal of Mathematics and Mathematical Sciences, 1990 A new class of contact manifolds (carring a global non-vanishing timelike vector field) is introduced to establish a relation between spacetime manifolds and contact structures.
K. L. Duggal
doaj +1 more source
An observation on n-permutability [PDF]
, 2013 We prove that in a regular category all reflexive and transitive relations are symmetric if and only if every internal category is an internal groupoid.
Martins-Ferreira, Nelson +2 more
core +1 more source