Results 61 to 70 of about 105,061,129 (288)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Annals of Glaciology, 2018 The medium-high mountain ranges of Western Europe are undergoing rapid socio-environmental changes. The aim of this study is to show that their landscape can be strongly shaped by the actions of avalanche activity, humans and climate.
Florie Giacona +8 more
doaj +1 more source
On some strongly regular relations on hyperrings
, 2018 In this paper first by the fact that the relation $α^*$ is the transitive closure of two its subrelations we introduce and analyze a binary relation $λ^*_e$ on a hyperring such that the derived ring is a unitary ring. Next we introduce and study the notion of $λ_e$-parts in a hyperring and we characterize $λ_e$-parts in a $λ_e$-strong hyperring $R ...
openaire +2 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Bounded Domains of Generalized Riesz Methods with the Hahn Property
Journal of Function Spaces and Applications, 2013 In 2002 Bennett et al. started the investigation to which extent sequence spaces are determined by the sequences of 0s and 1s that they contain.
Maria Zeltser
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cells, 2019 Adipose tissue accumulation is an independent and modifiable risk factor for cardiovascular disease (CVD). The recent CVD European Guidelines strongly recommend regular physical exercise (PE) as a management strategy for prevention and treatment of CVD ...
Leonardo Sandrini +7 more
doaj +1 more source
Selenium deficiency is linearly associated with hypoglycemia in healthy adults
Redox Biology, 2020 Objective: The trace element selenium (Se) is needed for regular biosynthesis of selenoproteins, which contribute to antioxidative defense systems and affect redox-regulated signaling.
Yue Wang +6 more
doaj +1 more source
Strongly Regular Graphs with Maximal Energy [PDF]
The energy of a graph is the sum of the absolute values of the eigenvalues of its adjacency matrix. Koolen and Moulton have proved that the energy of a graph on n vertices is at most n(1 + √n)/2, and that equality holds if and only if the graph is ...
Haemers, W.H.
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