Results 61 to 70 of about 114,902 (251)
Cells, 2019 Adipose tissue accumulation is an independent and modifiable risk factor for cardiovascular disease (CVD). The recent CVD European Guidelines strongly recommend regular physical exercise (PE) as a management strategy for prevention and treatment of CVD ...
Leonardo Sandrini +7 more
doaj +1 more source
Selenium deficiency is linearly associated with hypoglycemia in healthy adults
Redox Biology, 2020 Objective: The trace element selenium (Se) is needed for regular biosynthesis of selenoproteins, which contribute to antioxidative defense systems and affect redox-regulated signaling.
Yue Wang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Abstract and Applied Analysis, 2012 Let {𝑡𝑛}⊂(0,1) be such that 𝑡𝑛→1 as 𝑛→∞, let 𝛼 and 𝛽 be two positive numbers such that 𝛼+𝛽=1, and let 𝑓 be a contraction. If 𝑇 be a continuous asymptotically pseudocontractive self-mapping of a nonempty bounded closed convex subset 𝐾 of a real reflexive ...
Xionghua Wu +3 more
doaj +1 more source
Serum visfatin in chronic renal failure patients on maintenance hemodialysis: A correlation study
The Egyptian Journal of Internal Medicine, 2013 Background and aim of work Endothelial dysfunction, atherosclerosis, and cardiovascular disease are strongly linked to chronic kidney disease. It has been hypothesized that visfatin may play an important role in uremia-related atherosclerosis and the ...
Abdel Wahab M Lotfy +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Equivalent Standard Forms of a Class of Tropical Matrices and Centralizer Groups
MathematicsIn this paper, the equivalent standard forms of tropical idempotent strongly definite matrices are introduced. In particular, the observation of the equivalent standard forms of tropical idempotent normal matrices is given.
Yanliang Cheng
doaj +1 more source
Diversity, 2020 The knowledge on the hard bottom polychaete assemblages in the Northern Adriatic Sea, a Mediterranean region strongly affected by environmental pressures, is scarce and outdated.
Barbara Mikac +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
PLoS ONE, 2014 BackgroundEcological monitoring and sampling optima are context and location specific. Novel applications (e.g. biodiversity monitoring for environmental service payments) call for renewed efforts to establish reliable and robust monitoring in ...
Darren Norris +2 more
doaj +1 more source