Results 31 to 40 of about 13,562 (260)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A modified method to eliminate 210Bi interference in the analysis of 90Sr by extractive chromatography

He jishu, 2022
Background210Bi is one of the most important interferences in the analysis of 90Sr by extractive chromatography. It is verified by the leaching curve that bismuth and yttrium are completely adsorbed on the chromatographic column in the bis(2-ethylhexyl ...
LI Meili, LI Qiaoqin, DENG Yuyang, QIN Lianjing, DENG Fei   +4 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Measurement of Strontium-90 in the Persian Gulf Fish by Extraction Chromatography with Sr-resin and Liquid Scintillation Counter

Iranian South Medical Journal, 2020
Background: Despite its beneficial effects on human life, the nuclear industry has its own risks. Strontium 90 (90Sr) is one of the most dangerous radionuclides produced by the uranium 235 fission, and replaces the bone calcium in the human body, which ...
Maryam Firouzabadi, Hossein Jalali Jahromi, Hossein Anaraki Ardakani   +2 more
doaj  

CRITERIA FOR THE PROTECTION OF POPULATION AFTER RADIATION ACCIDENT: FOOD CONSUMPTION STRUCTURE AND PECULIARITIES OF THE INTERNAL DOSES FORMATION OF VARIOUS AGE GROUPS OF THE POPULATION OF THE RUSSIAN FEDERATION

Радиационная гигиена, 2018
The aim of the work is to assess the compliance of the possible doses to the population of the Russian Federation, calculated on the basis of current data on the levels of food consumption with the activity concentration corresponding to the intervention
V. S. Repin
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

DYNAMICS OF THE RADIOACTIVE POLLUTION IN THE SURFACE LAYER OF SOILS IN BULGARIA TWENTY YEARS AFTER THE CHERNOBYL NUCLEAR POWER PLANT ACCIDENT [PDF]

Journal of Central European Agriculture, 2008
The twenty years period past after the contamination with radionuclides in 1986, as a result of the accident in the Chernobyl’s NPP, allowed the accumulation of rich data base for the radiation status of the soils in Bulgaria.
I YORDANOVA, D STANEVA, TZ BINEVA, N STOEVA   +3 more
doaj  

Actual problems of food safety for the population living in the contaminated areas due to the Chernobyl disaster in the context of food security

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2019
The purpose of the research was to determine the current problems of food safety for the population received from radioactively contaminated as a result of the Chernobyl disaster.
V. A. Kotelevych
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The Preparation of 90Y Generator with Hydrated Manganese Dioxide

Journal of Isotopes, 2021
The adsorption behaviors of hydrated manganese oxide (HMD) for Strontium and Yttrium in hydrochloric acid and nitric acid solutions were studied. HMD does not adsorb Strontium in various concentrations of hydrochloric acid and nitric acid solutions.
YIN Bangshun;DENG Qimin;PAN Junnan;CHENG Zuoyong
doaj   +1 more source