Results 81 to 90 of about 965,004 (336)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Energy consumption structural adjustment and carbon neutrality in the post-COVID-19 era. [PDF]

Struct Chang Econ Dyn, 2021
Yang C, Hao Y, Irfan M.
europepmc   +1 more source

Price Adjustment and Market Structure [PDF]

The Economic Journal, 1979
The present thesis is concerned with the relationship between price adjustments in response to changes in economic conditions and industrial market structure. Its point of departure consists of abandoning the time-honoured assumption that firms in industrial markets act as if they were price takers. Instead, attention is focused on the determinants
openaire   +1 more source

Adjustment Capacity of Korean Farm Household [PDF]

Structural adjustment is defined as the farm household’s behavior of changing its existing farm asset distribution toward more specialized or diversified directions.
Kim, Hanho, Kim, Jae-Kyung
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

An Assessment of the Impact of "The Structural Adjustment Programme" on the Poultry Industry in Nigeria [PDF]

Tropicultura, 1996
The "Structural Adjustment Programme" (SAP) was introduced in 1986 to restructure and diversify the productive base of Nigerian economy, increase domestic food production, agricultural raw materials and enhance non-oil exports.
Eronmwon Guobadia, E.
doaj  

Using dual exonucleases to finely distinguish structural adjustment of aptamers for small-molecule detection. [PDF]

RSC Adv, 2021
Wang L, Zhou H, Yan K, Xu P, Di B, Hu C, Su M.   +6 more
europepmc   +1 more source

The Effect of IMF and World Bank Programmes on Poverty [PDF]

poverty, structural adjustment, economic growth, income ...
Easterly, William
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source