Results 101 to 110 of about 972,404 (306)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Structural Adjustment and Sociocentrism: The Discourse of Governance
Revista Administración Pública y Sociedad, 2016 The paper presents a series of visions, strategies and instruments approach that gained momentum in the mid-90s, from social decay and economic volatility that led to structural adjustment policies.The new visions dyeing the centrality of the individual ...
Horacio Cao +2 more
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The impact of farmland readjustment and consolidation on structural adjustment: The case of Niigata, Japan [PDF]
Improving agricultural productivity is a pressing challenge for rapidly growing economies. Farmland concentration among core famers is instrumental for reaping the economies of scale.
Arimoto, Yutaka
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
An overview of education: the management of public education [PDF]
Revista Electrónica Interuniversitaria de Formación del Profesorado, 2010 The article reviews the state of education in Spain and the most relevant trends arising from the current adjustment policies and neoliberal tendencies, which call into question the very existence of the public school system.
Beatriz Quirós Madariaga
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Euler-equation estimation for discrete choice models: a capital accumulation application [PDF]
This paper studies capital adjustment at the establishment level. Our goal is to characterize capital adjustment costs, which are important for understanding both the dynamics of aggregate investment and the impact of various policies on capital ...
John Haltiwanger +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Structural adjustment and forest resources - the impact of World Bank operations [PDF]
Over two decades, the World Bank has undertaken many structural adjustment operations withgovernments of developing countries. During negotiations for structural adjustment loans (SALs), partner governments agree to specific policy reforms, whose ...
Pandey, Kiran D., Wheeler, David
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Structural Adjustment, Global Trade and the New Political Economy of Development
Lahore Journal of EconomicsBiplab Dasgupta. Structural Adjustment Global Trade and the New Political Economy of Development. New Delhi. Sage Publications. 1998. Price Indian Rupees 450 (hardback).
Biplab Dasgupta.
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