Results 121 to 130 of about 972,404 (306)
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Gender and Structural Adjustment in Pakistan
Lahore Journal of EconomicsWe review the change in the socio-economic condition of women during the intensive period of structural adjustment (1987/88 onwards) in their role as producers, as home managers and as mothers.
Shahrukh Rafi Khan, Mehnaz Ahmad
doaj
Public sector management issues in structural adjustment lending [PDF]
This paper reviews the Bank's experience in implementing public sector management reforms through structural adjustment lending. The study focuses on those institutional aspects of adjustment that deal with"macro-management"issues related to improvements
Nunberg, Barbara
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Structural Adjustment and Health in Pakistan
Lahore Journal of EconomicsGovernment health expenditures as a percentage of GDP have declined in Pakistan, though not in absolute real terms, over the structural adjustment period. Progress over this period is evident on a number of health indicators.
Shahrukh Rafi Khan, Sajid Kazmi
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Pakistan’s Health Care Under Structural Adjustment
Lahore Journal of EconomicsThe health sector in Pakistan is replete with multifarious problems. It is not responding to the needs of the masses in a way that would provide high-quality care to all in need. Despite the announcements our governments make about health care each year,
Nina Gera
doaj
Structural Adjustments And Their Effects: Is There A Way Out For Africa? [PDF]
The IMF and World Bank have over the years gained a stronghold in African economic policies. This is mainly due to the borrowing and lending relationship between the continent and these sister organizations.
Ofori, Eunice
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Asymmetric Space Market Adjustment in the London Office Market [PDF]
Earlier estimates of the City of London office market are extended by considering a longer time series of data, covering two cycles, and by explicitly modeling of asymmetric space market responses to employment and supply shocks.
Bryan MacGregor +2 more
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