Results 111 to 120 of about 972,404 (306)

Firm-level adjustment costs and aggregate investment dynamics – Estimation on Hungarian data [PDF]

open access: yes
This paper uses Hungarian data to estimate the structural parameters of a firm-level investment model with a rich structure of adjustment costs, and analyzes whether non-convex adjustment costs have any effect on the aggregate investment dynamics.
Ádám Reiff
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The macroeconomic underpinnings of adjustment lending [PDF]

open access: yes
Drawing on conditionality and implementation information for 184 World Bank adjustment loans to 62 countries during the 1980s, the authors examine the macroeconomic underpinnings of Bank supported adjustment programs.
Jaspersen, Fred, Shariff, Karim
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

AGRICULTURAL STRUCTURAL ADJUSTMENT TO GOVERNMENT POLICIES: EMPIRICAL EVIDENCE [PDF]

open access: yes
Economic theory alone cannot predict the impacts of government payments on farm structure. We estimate a 5-equation model for the 1978-96 period to measure the impacts using state micro and macro data sets.
Ahearn, Mary Clare   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Structural Adjustment, Labour and the Poor in Pakistan

open access: yesLahore Journal of Economics
In this paper we cite evidence regarding the likely impact of IMF/World Bank policies on labour and the poor in Pakistan. Our findings show that since the 1987 bout of structural adjustment, public sector employment has decreased while wages have been ...
Shahrukh Rafi Khan, Safiya Aftab
doaj  

Received wisdom and beyond: Lessons from fiscal consolidation in the EU [PDF]

open access: yes
The paper examines consolidation episodes in the EU since 1970 with a view to shedding light on the factors that determine the success or failure of fiscal adjustment.
Alessandro Turrini, Martin Larch
core  

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

International Evidence on the Demand for Money [PDF]

open access: yes
One of the current questions in the literature on the demand for money is whether the adjustment of actual to desired money holdings is in nominal or real terms.
Ray C. Fair
core  

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