Results 241 to 250 of about 26,806,177 (307)

Physicochemical fingerprinting reveals convergent evolutionary determinants of enterovirus A71 neurovirulence through integrative machine learning and structural analysis. [PDF]

Virus Res
Wang X, Li F.
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Integrating machine learning and structural analysis to decipher benzo[a]pyrene-induced bladder cancer networks. [PDF]

Discov Oncol
Zhao X, Qin R, Shen C, Hu D, Li C, Liu C, Ge H, Wang Y.   +7 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Enhancing reliability and automation of LLM-based structural analysis using a hybrid multi-agent pipeline. [PDF]

Sci Rep
Heo S.
europepmc   +1 more source

Structural analysis of the flexibility of the Ubl2 domain within the papain-like protease of SARS-CoV-2. [PDF]

Acta Crystallogr F Struct Biol Commun
Freiherr von Scholley GL, Schaefer M, Tully MD, Hograindleur MA, Soler-López M, Hillig RC, Mueller-Dieckmann C, Kandiah E.   +7 more
europepmc   +1 more source

Nanoscale morphological and structural analysis of round and donut oligomers formed by C-terminal domain of TDP-43.

Phys Chem Chem Phys
Pickett D, Purvinsh Y, Skrehot JT, Warren D, Kurouski D.   +4 more
europepmc   +1 more source

Cyclin-dependent kinase-inhibitor screening and structural analysis identify a CDK-like kinase candidate in Naegleria fowleri. [PDF]

Parasit Vectors
Kim MJ, No JH.
europepmc   +1 more source

Does Age Matter? A Comparison of Personality Profiles in Adult and Older Patients with Cancer Using the Structural Analysis of Social Behavior (SASB). [PDF]

Healthcare (Basel)
Spatuzzi R, Giulietti MV, Fabbietti P, Vespa A.   +3 more
europepmc   +1 more source

Structural Analysis and Inhibitor Modeling of Bacterioferritin From Brucella abortus. [PDF]

Proteins
Liu L, Harmon EK, Craig JK, Yao H, Battaile KP, Johnson DK, Subramanian S, Van Voorhis WC, Rivera M, Lovell S.   +9 more
europepmc   +1 more source