Results 221 to 230 of about 3,177,476 (315)

Structural analysis of antigenic variation and adaptive evolution of the H5N1 neuraminidase gene. [PDF]

PLoS Comput Biol
Adegbaju MS, Owo-Odusi O, Wirtz ET, Morenikeji OB, Ojurongbe O, Thomas BN.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Mapping surgical deserts of cardiovascular training in Latin America: A geospatial and structural analysis. [PDF]

JTCVS Open
Cubas WS, Gundelach J, Montes L, Hernández M, Cubas S, Vota CS, Montero JA, Soca G, Dayan V, Chu MWA.   +9 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Enzymatic saccharification of Typha domingensis biomass: optimization and structural analysis. [PDF]

BMC Biotechnol
Zaki S, Kayani HA, Ejaz U, Alorabi M, Alanazi AK, Naz S, Sohail M, Abideen Z.   +7 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

In Silico Functional and Structural Analysis of <i>STAT4</i> Variants of Uncertain Significance. [PDF]

Genes (Basel)
Bravo-Villagra KM, Maciel-Cruz EJ, Martínez-Contreras RM, Gutiérrez-Hurtado IA, Vizcaíno-Quirarte AM, Muñoz-Valle JF, López-Quintero A.   +6 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Comparative immunogenic and structural analysis of virus-like particle and inactivated whole-virion vaccines against enterovirus D68. [PDF]

Mol Ther Nucleic Acids
Senpuku K, Kunishima Y, Hirose M, Karaki T, Taniguchi K, Kataoka-Nakamura C, Hirai T, Yasuda K, Kuroda E, Kato T, Ito T, Yoshioka Y.   +11 more
europepmc   +1 more source