Results 201 to 210 of about 6,922,711 (307)

Global comparative structural analysis of responses to protein phosphorylation. [PDF]

Nat Commun
Correa Marrero M, Mello VH, Sartori P, Beltrao P.   +3 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

A Computational Structural Analysis of Host Insertions in the Polyproline Region of the Hepatitis E Virus pORF1 Polyprotein. [PDF]

Viruses
Jeanne N, Paronetto O, Dimeglio C, Abravanel F, Lhomme S, Brut M, Izopet J.   +6 more
europepmc   +1 more source

Structure analysis of bow structure

, 2015
The bow structure presents a significant portion of the hull structure weight, cost and fabrication time. In this thesis, with the purpose of the reduction of the weight, we arrange three of the panel configurations of the ship bow we have definited in different way, changing optimal parameters we have studied such as stiffener direction, stiffener ...
openaire   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Machine Vision-Enabled Octahedral Network Reconstruction and Structural Analysis of Perovskite Quantum Dots. [PDF]

ACS Nano
Du G, Zhang H, Bian T, Wang W, Hu L, Liu Y, Zhan Z, Liu S, Li Y, He X, Huang C, Kong Y, Hao L, Wang J, Zhou N, Tu B, Zhu C, Gong JJ, Wu T, Yin J, Lin Z, Cai S.   +21 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Design and thermo-structural analysis of multiple composite layers with ablative materials for passive thermal protection systems. [PDF]

Sci Rep
Park J, Kim Y, Cha JH, Kim S, Choi O, Kim DC.   +5 more
europepmc   +1 more source

Structural Analysis of a Scissor Structure

Structural Analysis of a Scissor Structure
This research is supported by the Grantin-Aid for Challenging Exploratory Research of the Japan Society for the Promotion of Science; KAKENHI Grant Number JP18K18888. The developing and research of the Mobile bridge are supported by the Grant-in-Aid for Scientific Research (A) of the Japan Society for the Promotion of Science; KAKENHI Grant Number ...
openaire  

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source