Results 191 to 200 of about 3,177,476 (315)

Rheological and Structural Analysis of Hyaluronic Acid Fillers Used for Chin Augmentation. [PDF]

Dermatol Ther (Heidelb)
Carbone AC, Neves MLBB, Zinco AG, Nayak VV, de Sousa Mendes LA, De Marchi El Assad A, Câmara-Souza MB, Teixeira S, Machado Filho DA, Murakami FS, De la Torre Canales G.   +10 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Explainable hybrid CNN-transformer with self-supervised learning for structural analysis of paranasal sinus CT. [PDF]

Front Comput Neurosci
Ullah N, Algamdi SA, Sadad T.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Mechanistic and Structural Analysis of Aflatoxin B1 Degradation by <i>Bacillus safensis</i> Multicopper Oxidase. [PDF]

Foods
Xiong D, Yang J, Li P, Yang S, Long M.
europepmc   +1 more source

THE FORMAL LOGIC OF TESTING STRUCTURAL CHANGE IN MEAT DEMAND: A METHODOLOGICAL ANALYSIS

In the past two decades, the profession has expended valuable resources testing structural change in meat demand with mixed results. Overlooked to date is a fundamental methodological problem that transcends all of the methods of testing for structural ...
Davis, George C.
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Retraction of "Tuning the Magnetic Behavior of Zinc Ferrite via Cobalt Substitution: A Structural Analysis". [PDF]

ACS Omega
Hussain M, Mehmood A, Ali F, Sandhu ZA, Raza MA, Sajid S, Sohaib M, Khan MT, Bhalli AH, Hussain A, Arshid MS, Mehboob N, Al-Sehemi AG.   +12 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Enhancing reliability and automation of LLM-based structural analysis using a hybrid multi-agent pipeline. [PDF]

Sci Rep
Heo S.
europepmc   +1 more source