Results 171 to 180 of about 3,177,476 (315)

Structural Analysis of Human LonP1 Protease Bound with the Native Substrate. [PDF]

Life (Basel)
Li M, Liu H, Zhang S, Gao Q, Li S, Wang J, Zhang K.   +6 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Structural analysis of Cu/Zn-superoxide dismutase linked to neurodegenerative disease by antibody-guided cryo-EM. [PDF]

Protein Sci
Shino Y, Muraki N, Kobatake Y, Kamishina H, Kosuge H, Nakakido M, Tsumoto K, Furukawa Y.   +7 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Comparing Laboratory and Synchrotron X-Ray CT for Structural Analysis of PEEK Orthopedic Implants. [PDF]

Biomimetics (Basel)
Qi M, Zhao Y, Chen J, Zhang S, Zhang J, Zhang X.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

IGANets: Isogeometric analysis networks and their applications to linear structural analysis problems. [PDF]

Eng Comput
Möller M, Obermair G, Singer I, Gollmann C, Reali A, Elgeti S.   +5 more
europepmc   +1 more source

Data Processing of Laser Scans Towards Applications in Structural Engineering

, 2009
This research is investigating the use of high resolution 3D terrestrial laser scanners as tools to capture geometric data of complex scenes for structural engineering applications. Laser scan technology is continuously improving, with commonly available
Walsh, Sara B., Sara B. Walsh, Jerome F. Hajjar, Hajjar, Jerome F.   +3 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Rapid Structural Analysis of Natural Products Using MicroED. [PDF]

Small
Lin J, Paz O, Unge J, Gonen T.
europepmc   +1 more source