Results 161 to 170 of about 3,177,476 (315)

Case study : structural health monitoring of timber bridges using dynamic frequency analysis (DFA)

, 2017
Australia has numerous ageing timber bridges in service. The structural efficiency of the majority of them have been impaired over time and their capacity is not known. There is, therefore, a critical need to develop new methods that will enable the load
Rashidi, Maria (R18339), Samali, Bijan (R17646), Azad, Amir (R18712), Ghodrat, Maryam (R18544), Zhu, Xinqun (R14089)   +4 more
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Chemical and structural analysis of a European hornet nest. [PDF]

Sci Rep
Jurczyková T, Caranová M, Kačík F, Čabalová I, Lapčák L, Říhová A, Zeidler A, Augustová P.   +7 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Structural Analysis of Tilvestamab in Complex with AXL. [PDF]

ACS Omega
Christakou E, Lopez AJ, Muruganandam G, Micklem D, Lorens JB, Kursula P.   +5 more
europepmc   +1 more source

Finite element analysis of push tests under elevated temperatures

, 2008
A three-dimensional push test model has been developed herein with a two dimensional temperature distribution analysis procedure based on the finite element method (FEM) and applied to steel-concrete composite beams.
Wong, Bill, Uy, Brian, Mirza, Olivia, Gad, Emad   +3 more
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

The Analysis of Hybrid Trie Structures.

, 1997
This paper provides a detailed analysis of various implementations of digital tries, including the "ternary search tries" of Bentley and Sedgewick. The methods employed combine symbolic uses of generating functions, Poisson models, and Mellin transforms.
Clément, Julien, Flajolet, Philippe, Vallée, Brigitte   +2 more
openaire   +3 more sources