Results 101 to 110 of about 1,254,731 (295)
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
A preliminary study of the nonlinearity of adhesive point-fixings in structural glass facades
Journal of Facade Design and Engineering, 2014 The recent demand for architectural transparency has drastically increased the use of glass material for structural purpose. However, connections between structural glass members represent one of the most critical aspects of glass engineering, due to ...
Jonas Dispersyn +3 more
doaj +1 more source
The social and structural architecture of the yeast protein interactome. [PDF]
Nature, 2023 Michaelis AC +6 more
europepmc +1 more source
Covalently bound substrate at the regulatory site triggers allosteric enzyme activation [PDF]
, 2008 The mechanism by which the enzyme pyruvate decarboxylase from yeast is activated allosterically has been elucidated. A total of seven three-dimensional structures of the enzyme, of enzyme variants or of enzyme complexes form two yeast species (three of ...
Georg Wille +5 more
core +1 more source
Modelling microgels with controlled structure across the volume phase transition
, 2019 Thermoresponsive microgels are soft colloids that find widespread use as model systems for soft matter physics. Their complex internal architecture, made of a disordered and heterogeneous polymer network, has been so far a major challenge for computer ...
Camerin, Fabrizio +7 more
core +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source
, 2013 Through different projects of the office, the paper explores which design strategies allow to address structure and architecture as two equally important aspects of one unique ambition in each project. The structural approaches are specific to each project. However, all procede from the a same attitude : structural principles are enounced at some point,
Vandenbulcke, Benoît, Fallon, Harold
openaire +4 more sources
The finite element machine: An experiment in parallel processing [PDF]
The finite element machine is a prototype computer designed to support parallel solutions to structural analysis problems. The hardware architecture and support software for the machine, initial solution algorithms and test applications, and preliminary ...
Adams, L. +4 more
core +1 more source
SchNet: A continuous-filter convolutional neural network for modeling quantum interactions [PDF]
, 2017 Deep learning has the potential to revolutionize quantum chemistry as it is ideally suited to learn representations for structured data and speed up the exploration of chemical space. While convolutional neural networks have proven to be the first choice
Chmiela, Stefan +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source