Results 81 to 90 of about 434,374 (261)

The impact of values and modelling method on the static-strength work of a typical scaffolding

Budownictwo i Architektura, 2014
This paper describes the results of static non-linear calculations in reference to a typical building scaffolding, in the case when the scaffolding is operated.
Ewa Błazik-Borowa, Jakub Gontarz
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Physics-Informed Surrogate Modelling in Fire Safety Engineering: A Systematic Review

Applied Sciences
Surrogate modelling is increasingly used in engineering to improve computational efficiency in complex simulations. However, traditional data-driven surrogate models often face limitations in generalizability, physical consistency, and extrapolation ...
Ramin Yarmohammadian, Florian Put, Ruben Van Coile   +2 more
doaj   +1 more source

Development of adhesion between two concretes during concrete hardening

Budownictwo i Architektura, 2009
The main factor influencing the bearing capacity in composite members is bond strength between concretes, because only effective joint between substrate and overlay ensure their full structural cooperation.
Anna Halicka, Dominika Franczak
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Unsteady Flow and Loading Characteristics of Rotating Spheres During Underwater Ejection

Journal of Marine Science and Engineering
This study systematically investigates the evolution of the flow field and cavitation behavior during the underwater launch of a rotating sphere. By comparing surface pressure distribution, cavitation evolution, flow separation locations, and re-entrant ...
Hao Xu, Mingyang Wang, Zhou Zhou, Tiezhi Sun, Guiyong Zhang   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Architecture & Research: A Possible Structure

, 2011
Revista Lusófona de Arquitectura e ...
openaire   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Cognitive Architectures for Conceptual Structures [PDF]

, 2011
The book Conceptual Structures: Information Processing in Mind and Machine surveyed the state of the art in artificial intelligence and cognitive science in the early 1980s and outlined a cognitive architecture as a foundation for further research and development.
openaire   +2 more sources