Results 71 to 80 of about 434,374 (261)

Determination of tensile strength of concrete and rocks by using the Brazilian test in the confrontation with the failure criteria

open access: yesBudownictwo i Architektura, 2014
The paper presents the analysis of the Brazilian compression tests considering the possibilities of determining the proper tensile strength. These analyses include the precise designation of the stress field without singularity at the point of ...
Jakub Gontarz, Jerzy Podgórski
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Strengthening Klein’s floor slabs with the use of current norms

open access: yesBudownictwo i Architektura, 2015
The paper presents the effectivity of using the steel-concrete floor slabs in existing buildings. Steel-concrete slabs described in this paper consist of old steel beams which are main structural members of the floor slabs and reinforced concrete slabs ...
Marcin Górecki   +1 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A preliminary study of the nonlinearity of adhesive point-fixings in structural glass facades

open access: yesJournal of Facade Design and Engineering, 2014
The recent demand for architectural transparency has drastically increased the use of glass material for structural purpose. However, connections between structural glass members represent one of the most critical aspects of glass engineering, due to ...
Jonas Dispersyn   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Issues of contemporary wind engineering and aerodynamics of building structures

open access: yesBudownictwo i Architektura, 2016
The paper reviews nowadays problems and issues of wind engineering and aerodynamics of building structures. The article mainly focuses on aerodynamics of building structures, shortly characterizing theoretical bases, which one must take into account when
Tomasz Lipecki, Paulina Jamińska
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Structure by Architecture: Structured Representations without Regularization

open access: yes, 2020
We study the problem of self-supervised structured representation learning using autoencoders for downstream tasks such as generative modeling. Unlike most methods which rely on matching an arbitrary, relatively unstructured, prior distribution for sampling, we propose a sampling technique that relies solely on the independence of latent variables ...
Felix Leeb   +5 more
openaire   +3 more sources

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