Results 51 to 60 of about 1,267,350 (294)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Pore structure of mortars containing limestone powder and natural pozzolan assessed through mercury intrusion porosimetry and dynamic vapour sorption

MATEC Web of Conferences, 2018
Pore structure characterization is a key aspect when studying the durability of cementitious materials. When supplementary cementitious materials (SCMs) are used changes in pore structure are expected, and the complexity of its analysis is increased. The
Alderete Natalia, Villagrán Yury, Mignon Arn, Snoeck Didier, De Belie Nele   +4 more
doaj   +1 more source

The impact of vibration on buildings: Problems and solutions [PDF]

E3S Web of Conferences
The article presents a comprehensive overview of a study investigating the influence of soil-foundation interaction on the natural frequencies and vibration safety of reinforced concrete cellular and frame buildings.
Kovrova Viktoriia, Volkova Viktoriia, Pakrastins Leonids   +2 more
doaj   +1 more source

Evaluation of the Hydraulic, Physical, and Mechanical Properties of Pervious Concrete Using Iron Tailings as Coarse Aggregates

Applied Sciences, 2020
Aggregates are a significant component of pervious concrete. Pervious concrete using iron tailings as coarse aggregates was prepared to study the feasibility of this approach.
Yan Tan, Yuntao Zhu, Henglin Xiao
doaj   +1 more source

Translating material and design space:Strategies to design with curved creased surfaces [PDF]

, 2009
This paper shares findings from the project DevA (Developable surfaces in Architecture), a research by design based project developed a collaboration between academic and industry partners. The project aims to investigate the use of curved sheet material
Asut, Serdar, Joseffson, Kristoffer, Ramsgaard Thomsen, Mette, Tamke, Martin   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Seismic vulnerability of Modern Architecture building's: Le Corbusier style: a case study [PDF]

, 2005
In Portugal, at the end of the World War II, a new generation of architects emerged, influenced by the Modern Movement Architecture, born in Central-Europe in the early twenties but now influenced also by the Modern Brazilian Architecture. They worked
Costa, A., Fonseca, J., Rodrigues, H., Tostões, A., Varum, H.   +4 more
core   +1 more source

Towards Consistency Management for a Business-Driven Development of SOA [PDF]

, 2013
The usage of the Service Oriented Architecture (SOA) along with the Business Process Management has emerged as a valuable solution for the complex (business process driven) system engineering.
Karim Dahman, Franc¸ois Charoy, Claude Godart
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source