Results 41 to 50 of about 1,267,350 (294)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Joint Training of a Convolutional Network and a Graphical Model for Human Pose Estimation [PDF]

open access: yes, 2014
This paper proposes a new hybrid architecture that consists of a deep Convolutional Network and a Markov Random Field. We show how this architecture is successfully applied to the challenging problem of articulated human pose estimation in monocular ...
Bregler, Christoph   +3 more
core  

The envirome and the connectome: exploring the structural noise in the human brain associated with socioeconomic deprivation [PDF]

open access: yes, 2013
Complex cognitive functions are widely recognized to be the result of a number of brain regions working together as large-scale networks. Recently, complex network analysis has been used to characterize various structural properties of the large scale ...
Batty, D.   +7 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Potential Architecture [PDF]

open access: yes, 2013
The exhibition brings together new work: sculpture, drawings and models created by Lucy + Jorge Orta during their research on new organic and modular architecture as a result of their collaborations with the Greenham partnership and other communities ...
Orta, Jorge, Orta, Lucy
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structures and Architecture [PDF]

open access: yes
From Wood to Tree explores designing with wood’s natural degradation processes. This case-study proposes a sustainable approach for reintegrating processed preprocessed lumber into forest ecosystems, highlighting the importance of deadwood in supporting nutrient cycling, fostering fungal growth, enhancing soil health and providing habitats for saplings,
Rinke, Mario, Hvejsel, Marie Frier
  +4 more sources

Nonlinear seismic analysis of masonry infilled RC frame structures [PDF]

open access: yesGrađevinski Materijali i Konstrukcije, 2019
Structures composed of different substructures and materials are a subject of great research and expert interest. It is the purpose of this research to develop an engineering approach for evaluation of seismic demands and to apply the methodology to ...
Mahmud Emin   +2 more
doaj  

Model Experimental Study of Carbon Fiber Heating Wire for Deicing and Snow Melting on a Bridge Deck

open access: yesAdvances in Civil Engineering, 2020
In order to use the carbon fiber heating wire more efficiently and safely, the influence of the built-in carbon fiber heating wires (CFHWs) on the temperature changes of the bridge deck is studied in this paper.
Yan Tan, Yuntao Zhu, Henglin Xiao
doaj   +1 more source

Internal structure of structurally stitched NCF preform [PDF]

open access: yes, 2006
The paper addresses the experimental investigation of the unit cell architecture in a structurally stitched multilayer carbon-fibre preform. Each layer is a multiaxial multiply non-crimp fabric (NCF) knit with a non-structural stitching.
Drechsler, K.   +5 more
core   +1 more source

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